Perioperative management of pyoderma gangrenosum.
Pyoderma gangrenosum (PG) classically presents with an acute inflammatory stage, characterized by rapid evolution of painful ulcerations. The pathergy associated with PG lesions complicates disease management. Although PG is commonly treated with immunosuppression, some patients have refractory noni...
| Publicado en: | Journal of the American Academy of Dermatology Vol. 83; no. 2; pp. 369 - 375 |
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| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Elsevier B.V.
Aug2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=144546152&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 144546152 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01909622 1ZF jtl: Journal of the American Academy of Dermatology issn: 01909622 maglogo: N pubinfo: dt: Aug2020 vid: 83 iid: 2 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 144546152 144546152 NLM31927079 144546152 10.1016/j.jaad.2020.01.002 NLM31927079 144546152 ppf: 369 ppct: 6 formats: tig: atl: Perioperative management of pyoderma gangrenosum. aug: au: Haag, Carter K. Bacik, Lindsay Latour, Emile Morse, Daniel C. Fett, Nicole M. Ortega-Loayza, Alex G. affil: Department of Dermatology, Oregon Health & Science University, Center for Health & Healing, Portland, Oregon sug: subj: Recurrence Prevention and Control Surgery, Operative Methods Perioperative Care Methods Pyoderma Gangrenosum Surgery Treatment Outcomes Recurrence Scales Human ab: Pyoderma gangrenosum (PG) classically presents with an acute inflammatory stage, characterized by rapid evolution of painful ulcerations. The pathergy associated with PG lesions complicates disease management. Although PG is commonly treated with immunosuppression, some patients have refractory noninflammatory ulcers. In this subpopulation, there are case reports of successful surgical treatment. However, there is no consensus on optimal perioperative treatment for patients with PG undergoing surgery of any kind, PG related or otherwise. Therefore, we conducted a comprehensive literature review describing perioperative management practices and risk factors that may predict response to surgical intervention. We identified 126 cases of surgical intervention in patients with active PG; among these, only 16.7% experienced postoperative disease progression. No perioperative treatments or clinical risk factors were identified as statistically significant predictors of disease recurrence. Although limited by case series design and publication bias, this study is a valuable means of hypothesis generation for this rare condition. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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