European Biological Variation Study (EuBIVAS): within- and between-subject biological variation estimates of β-isomerized C-terminal telopeptide of type I collagen (β-CTX), N-terminal propeptide of type I collagen (PINP), osteocalcin, intact fibroblast growth factor 23 and uncarboxylated-unphosphorylated matrix-Gla protein—a cooperation between the EFLM Working Group on Biological Variation and the International Osteoporosis Foundation-International Federation of Clinical Chemistry Committee on Bone Metabolism

Summary: We have calculated the biological variation (BV) of different bone metabolism biomarkers on a large, well-described cohort of subjects. BV is important to calculate reference change value (or least significant change) which allows evaluating if the difference observed between two consecutiv...

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Bibliographic Details

Published in:	Osteoporosis International Vol. 31; no. 8; pp. 1461 - 1471
Main Authors:	Cavalier, E., Lukas, P., Bottani, M., Aarsand, A.K., Ceriotti, F., Coşkun, A., Díaz-Garzón, J., Fernàndez-Calle, P., Guerra, E., Locatelli, M., Sandberg, S., Carobene, A., on behalf of the European Federation of Clinical Chemistry and Laboratory Medicine Working Group on Biological Variation and IOF-IFCC Committee on Bone Metabolism, Åkesson, Kristina, Bhattoa, Harjit Pal, Bruyère, Olivier, Cooper, Cyrus, Eastell, Richard, Garnero, Patrick, Heijboer, Annemieke
Format:	equations & formulas research tables/charts Journal Article
Published:	Springer Nature Aug2020
Online Access:	View this record in EBSCOhost