Anaesthetic management of a three-month-old baby for cervical limited dorsal myeloschisis repair using propofol and alfentanil infusions guided by pharmacokinetic simulation software: A case report.

We present an uncommon case of limited dorsal myeloschisis in a 3-month-old infant requiring repair guided by intraoperative neuromonitoring (IONM) and therefore avoidance of volatile anaesthetic agents. The case presented challenges in positioning, airway management, a lack of age appropriate pharm...

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Publicado en:Southern African Journal of Anaesthesia & Analgesia Vol. 25; no. 6; pp. 32 - 36
Autores principales: Coetzee, E., Gray, R., Hollman, C., Enslin, J. M. N., Coetzee, J. F.
Formato: Journal Article
Publicado: Medpharm Publications (Pty) Ltd. 2019
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Anaesthetic management of a three-month-old baby for cervical limited dorsal myeloschisis repair using propofol and alfentanil infusions guided by pharmacokinetic simulation software: A case report.
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          Coetzee, E.
          Gray, R.
          Hollman, C.
          Enslin, J. M. N.
          Coetzee, J. F.
        affil: Department of Anaesthesia and Perioperative Medicine, Red Cross War Memorial Children's Hospital, University of Cape Town, South Africa
      sug:
      ab: We present an uncommon case of limited dorsal myeloschisis in a 3-month-old infant requiring repair guided by intraoperative neuromonitoring (IONM) and therefore avoidance of volatile anaesthetic agents. The case presented challenges in positioning, airway management, a lack of age appropriate pharmacokinetic models in target-controlled infusion (TCI) syringe pumps and unavailability of remifentanil, considered to be an essential drug in this setting. We overcame these challenges using manually controlled infusions of propofol and alfentanil guided by pharmacokinetic simulation software (Stelsim).
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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