Correlation between Body Mass Index and Periprosthetic Joint Infection following Total Joint Arthroplasty: A protocol for systematic review and meta analysis.
Background: Despite rapid reports on the correlation between body mass index (BMI) and periprosthetic joint infection (PJI) after total joint arthroplasty, some have conducted regression tests or meta-analyses with controversial results. In this study, we systematically meta-analyzed relevant trials...
| Publicado en: | Medicine Vol. 99; no. 24; pp. 1 - 12 |
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| Autores principales: | , , , , , , , , , , , , , , , |
| Formato: | protocol tables/charts Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
6/12/2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=144660650&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 144660650 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00257974 2S6 jtl: Medicine issn: 00257974 maglogo: N pubinfo: dt: 6/12/2020 vid: 99 iid: 24 pid: 433 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 144660650 144660650 NLM32541477 144660650 10.1097/MD.0000000000020549 NLM32541477 144660650 ppf: 1 ppct: 11 formats: tig: atl: Correlation between Body Mass Index and Periprosthetic Joint Infection following Total Joint Arthroplasty: A protocol for systematic review and meta analysis. aug: au: Jing-Li Xu Zheng-Rong Liang Bing-Lang Xiong Qi-Zhao Zou Tian-Ye Lin Peng Yang Da Chen Qing-Wen Zhang Xu, Jing-Li Liang, Zheng-Rong Xiong, Bing-Lang Zou, Qi-Zhao Lin, Tian-Ye Yang, Peng Chen, Da Zhang, Qing-Wen affil: Zhanjiang first hospital of Traditional Chinese Medicine, Zhanjiang. sug: subj: Body Mass Index Arthritis, Infectious Etiology Obesity Complications Prosthesis-Related Infections Etiology Meta Analysis Systematic Review ab: Background: Despite rapid reports on the correlation between body mass index (BMI) and periprosthetic joint infection (PJI) after total joint arthroplasty, some have conducted regression tests or meta-analyses with controversial results. In this study, we systematically meta-analyzed relevant trials and carefully evaluated the correlation for verification.Methods: Literature on the correlation between BMI and PJI following total joint arthroplasty was retrieved in PubMed, Embase and Cochrane Library due September 2019. Stata 13.0 software was adopted for data synthesis and analyses of publication bias and sensitivity. Random-effect models were used to summary the overall estimate of the multivariate adjusted odds ratio (OR)/hazard ratio/rate ratio with 95% confidence intervals (CIs).Results: A total of 29 observational studies representing 3,204,887 patients were included. The meta-analysis revealed that the risk of postoperative PJI significantly increased by 1.51 times in the obese group (OR = 1.51; 95% CI = 1.30-1.74 for the obese group vs. the non-obese group), and by 3.27 times in the morbid obese group (OR = 3.27; 95% CI = 2.46-4.34 for the morbid obese group vs the non-morbid obese group). A significant association remained consistent, as indicated by subgroup analyses and sensitivity analyses.Conclusion: Our findings demonstrate that postoperative PJI is positively correlated with BMI, with obese patients showing a greater risk of developing PJI than non-obese patients. Similarly, morbid obese patients present a higher risk of PJI than non-morbid obese patients. However, this conclusion needs to be corroborated by more prospective studies. pubtype: Academic Journal doctype: protocol tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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