Structural Optimization of the Diarylurea PSNCBAM-1, an Allosteric Modulator of Cannabinoid Receptor 1.

• PSNCBAM-1 is an allosteric modulator of the cannabinoid receptor 1. • Derivatives of PSNCBAM-1 were made, to reduce the total rings in the structure. • Several derivatives maintained allosteric activity, as shown by binding experiments. • Some calculated physicochemical properties for these deriva...

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Bibliographic Details
Published in:Current Therapeutic Research Vol. 92
Main Authors: Dopart, Rachel, Immadi, Sri Sujana, Lu, Dai, Kendall, Debra A.
Format: research tables/charts Journal Article
Published: Elsevier B.V. 2020
Online Access:View this record in EBSCOhost