Microarray Normalization Revisited for Reproducible Breast Cancer Biomarkers.

Precision medicine for breast cancer relies on biomarkers to select therapies. However, the reliability of biomarkers drawn from gene expression arrays has been questioned and calls for reassessment, in particular for large datasets. We revisit widely used data-normalization procedures and evaluate...

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Bibliographic Details
Published in:BioMed Research International pp. 1 - 28
Main Authors: Kenn, Michael, Cacsire Castillo-Tong, Dan, Singer, Christian F., Cibena, Michael, Kölbl, Heinz, Schreiner, Wolfgang
Format: research tables/charts Journal Article
Published: Wiley-Blackwell 8/6/2020
Online Access:View this record in EBSCOhost