Strain Curve Classification Using Supervised Machine Learning Algorithm with Physiologic Constraints.

Speckle tracking echocardiography (STE) enables quantification of myocardial deformation by a generation of spatiotemporal strain curves or time-strain curves (TSCs). Currently, only assessment of peak global longitudinal strain is employed in clinical practice because of the uncertainty in the accu...

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Publicado en:Ultrasound in Medicine & Biology Vol. 46; no. 9; pp. 2424 - 2439
Autores principales: Yahav, Amir, Zurakhov, Grigoriy, Adler, Omri, Adam, Dan
Formato: research Journal Article
Publicado: Elsevier B.V. Sep2020
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: Ultrasound in Medicine & Biology
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      dt: Sep2020
      vid: 46
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      pub: Elsevier B.V.
      place: New York, New York
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        10.1016/j.ultrasmedbio.2020.03.002
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        atl: Strain Curve Classification Using Supervised Machine Learning Algorithm with Physiologic Constraints.
      aug:
        au:
          Yahav, Amir
          Zurakhov, Grigoriy
          Adler, Omri
          Adam, Dan
        affil: Faculty of Biomedical Engineering, Technion—Israel Institute of Technology, Haifa, Israel
      sug:
        subj:
          Heart Physiology
          Echocardiography Methods
          Female
          Adult
          Human
          Male
          Heart Function Tests
          Comparative Studies
          Multicenter Studies
          Evaluation Research
          Validation Studies
          Scales
          Adult: 19-44 years
          Female
          Male
      ab: Speckle tracking echocardiography (STE) enables quantification of myocardial deformation by a generation of spatiotemporal strain curves or time-strain curves (TSCs). Currently, only assessment of peak global longitudinal strain is employed in clinical practice because of the uncertainty in the accuracy of STE. We describe a supervised machine learning, physiologically constrained, fully automatic algorithm, trained with labeled data, for classification of TSCs into physiologic or artifactual classes. The data set of 415 healthy patients, with three cine loops per patient, corresponding to the three standard 2-D longitudinal views, was processed using a previously published, in-house STE software termed K-SAD. We report an accuracy of 86.4% for classifying TSCs as physiologic, artifactual and undetermined curves. The positive predictive value for a physiologic strain curve is 89%. This is as a necessary step for a similar separation of pathologic conditions, to allow full utilization of the temporal information concealed in layer-specific segmental TSCs.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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