Comorbidity Clusters and Healthcare Use in Individuals With COPD.

Background: Individuals who share the same comorbidity profile are usually similar with regard to their disease severity, use of health care, and clinical outcomes. The identification of comorbidity clusters therefore bears prognostic information. The objective of this study was to identify and char...

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Publicado en:Respiratory Care Vol. 65; no. 8; pp. 1120 - 1128
Autores principales: Sklander Hansen, Nanna, Ängquist, Lars, Lange, Peter, Jacobsen, Ramune
Formato: research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. Aug2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2020
      vid: 65
      iid: 8
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      pub: Mary Ann Liebert, Inc.
      place: New Rochelle, New York
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        10.4187/respcare.07136
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        atl: Comorbidity Clusters and Healthcare Use in Individuals With COPD.
      aug:
        au:
          Sklander Hansen, Nanna
          Ängquist, Lars
          Lange, Peter
          Jacobsen, Ramune
        affil: Department of Public Health, University of Copenhagen, Copenhagen, Denmark
      sug:
        subj:
          Pulmonary Disease, Chronic Obstructive Complications
          Pulmonary Disease, Chronic Obstructive Prognosis
          Comorbidity Epidemiology
          Health Resource Utilization Evaluation
          Human
          Denmark
          Algorithms
          Cluster Analysis
          Descriptive Statistics
          Hypertension
          Adolescence
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Hospitalization
          Length of Stay
          Heart Diseases
          Socioeconomic Factors
          Registries, Disease
          Male
          Female
          Linear Regression
          Data Analysis Software
          Hypersensitivity
          Confidence Intervals
          Age Factors
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Background: Individuals who share the same comorbidity profile are usually similar with regard to their disease severity, use of health care, and clinical outcomes. The identification of comorbidity clusters therefore bears prognostic information. The objective of this study was to identify and characterize comorbidity clusters in individuals with COPD in Denmark. Methods: Data from the Danish national registers were used. The study population included all individuals ≥16 y old who lived in the Danish Capital Region on January 1, 2012, and were diagnosed with COPD (N = 70,274). Comorbid chronic conditions were identified using diagnostic algorithms. A 2-step cluster analysis was performed. Results: 81% of subjects with COPD had chronic comorbidities; the most common was hypertension (47.6%), and the least common was anxiety (0.1%). Three comorbidity clusters were identified. Cluster 1 contained 16% of the studied individuals with COPD, with all having heart disease in addition to the remaining comorbidities. Cluster 2 contained 30% of the studied individuals with COPD, of whom approximately 1 in 3 suffered from allergies, while the rest had no comorbidities. Cluster 3 contained 54% of the studied individuals with COPD, where all comorbidities but heart disease were represented. Cluster 1 contained the highest proportion of individuals over the age of 65 y, as well as the individuals with the lowest education. After adjusting for sociodemographic characteristics, individuals in Cluster 1 had the highest rates of hospitalizations and bed days. Conclusions: The presence of heart disease in individuals with COPD is a strong prognostic factor for socioeconomic and health vulnerability.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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