The association between diabetes and cognitive changes during aging.
Worldwide, we are observing a rising prevalence of dementia and mild cognitive impairments that often co-occur with the heightened incidence of non-communicable diseases in the elderly. It is suggested that type 2 diabetes and defects in glucose metabolism might predispose to poorer cognitive perfor...
| Published in: | Scandinavian Journal of Primary Health Care Vol. 38; no. 3; pp. 281 - 291 |
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| Main Authors: | , , , , , |
| Format: | research systematic review tables/charts Journal Article |
| Published: |
Taylor & Francis Ltd
Sep2020
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=145133966&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 145133966 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 02813432 BDB jtl: Scandinavian Journal of Primary Health Care issn: 02813432 maglogo: Y pubinfo: dt: Sep2020 vid: 38 iid: 3 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 145133966 145133966 145613294 145133966 10.1080/02813432.2020.1802140 145133966 ppf: 281 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: The association between diabetes and cognitive changes during aging. aug: au: Papunen, Sanna Mustakallio-Könönen, Anna Auvinen, Juha Timonen, Markku Keinänen-Kiukaanniemi, Sirkka Sebert, Sylvain affil: Centre for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland sug: subj: Cognition Evaluation Diabetes Mellitus Aging Human Female Male Aged Systematic Review PubMed Medline Diabetes Mellitus, Type 2 Quality Assessment Cognition Disorders Descriptive Statistics Aged: 65+ years Female Male ab: Worldwide, we are observing a rising prevalence of dementia and mild cognitive impairments that often co-occur with the heightened incidence of non-communicable diseases in the elderly. It is suggested that type 2 diabetes and defects in glucose metabolism might predispose to poorer cognitive performances and more rapid decline in old age. to address existing knowledge gaps in this area, we systematically reviewed the literature to identify whether patients with type 2 diabetes (T2DM) and pre-diabetes are at a higher risk of poorer cognitive performance, and whether the risk (if any) might affect specific cognitive abilities. We concentrated the review on elderly individuals (65 years or older) at intake. In total, 3251 original articles were retrieved, of which 17 met our inclusion and quality control criteria, which comprised 12 structured questions used to define the articles. 11 of 17 studies found a statistically significant decline in cognition among individuals who had T2DM or pre-diabetes compared to their non-diabetic counterparts. The association between diabetes and cognitive decline was not always clear, and the extent of the cognitive tests used seemed to have the greatest effect on the results. Focusing on a population age 65 years and over, we found insufficient evidence to support an association between pre-diabetes stages and mild cognitive impairment. However, there is consistent evidence to support diabetes as an independent risk factor for low cognitive ability in the elderly. Finally, we found insufficient evidence to support effect of T2DM on distinct cognitive ability due to the scarcity of comparable findings. pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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