Factors Related to Relapse in Patients with Substance-related Disorders under Methadone Maintenance Therapy: Decision Tree Analysis.

Objectives: We sought to determine the main factors related to relapse in patients with substance-related disorders (SRDs) who received methadone maintenance therapy (MMT) using decision tree (DT) analysis. Methods: We conducted a cross-sectional study of 4175 patients referred to the 45 MMT centers...

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Publicado en:Oman Medical Journal Vol. 35; no. 1; pp. 50 - 57
Autores principales: Moradinazar, Mehdi, Farnia, Vahid, Alikhani, Mostafa, Karyani, Ali Kazemi, Rezaei, Satar, Rezaeian, Shahab, Matin, Behzad Karami, Najafi, Farid
Formato: research tables/charts Journal Article
Publicado: Oman Medical Specialty Board 2020
Acceso en línea:Ver este registro en EBSCOhost
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        10.5001/omj.2020.07
        145219485
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        atl: Factors Related to Relapse in Patients with Substance-related Disorders under Methadone Maintenance Therapy: Decision Tree Analysis.
      aug:
        au:
          Moradinazar, Mehdi
          Farnia, Vahid
          Alikhani, Mostafa
          Karyani, Ali Kazemi
          Rezaei, Satar
          Rezaeian, Shahab
          Matin, Behzad Karami
          Najafi, Farid
        affil: Substance Abuse Prevention Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran
      sug:
        subj:
          Recurrence Risk Factors
          Substance Use Disorders Drug Therapy
          Methadone Therapeutic Use
          Risk Assessment
          Decision Trees
          Human
          Cross Sectional Studies
          Iran
          Persons with Substance Use Disorders
          Psychiatric Patients
          Interviews
          Descriptive Statistics
          Univariate Statistics
          Multiple Regression
          Algorithms
          Male
          Female
          Age Factors
          Street Drugs Economics
          Substance Abuse Epidemiology
          Drug Utilization
          Male
          Female
      ab: Objectives: We sought to determine the main factors related to relapse in patients with substance-related disorders (SRDs) who received methadone maintenance therapy (MMT) using decision tree (DT) analysis. Methods: We conducted a cross-sectional study of 4175 patients referred to the 45 MMT centers in Kermanshah province, west of Iran. We included all patients who were under MMT for at least one year. All information was collected through an interview by a psychologist. Descriptive statistics and univariate and multiple regression models were used in statistical analysis. The Gini index was calculated to determine the cut-off point of nodes. We used the Classification and Regression Trees algorithm to create the DT. Results: The relapse rate was 76.6% for all participants, with no significant gender differences. The DT resulted in a five-level model of significant factors affecting substance abuse relapse. These included lower cost for buying substances, lower age at first substance use, history of quitting substances without medication, frequency of substances utilization per month, and frequency of methadone therapy. Conclusions: Knowing the main factors associated with substance abuse relapse could be important for health care providers to make better decisions for improving the treatment outcomes of SRDs.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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