Biological and phytochemical studies on Capparis decidua (Forssk) Edgew from Cholistan desert.
The present work deals with the biological and phytochemical studies on Capparis decidua (Forssk) Edgew from Cholistan desert of Pakistan. Aerial and floral parts of C. decidua were collected and dried under shade. Powdered materials of each part of C. decidua were extracted with methanol separately...
| Publicado en: | Natural Product Research Vol. 34; no. 16; pp. 2315 - 2319 |
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| Autores principales: | , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Taylor & Francis Ltd
Aug2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=145255021&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 145255021 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14786419 RFT jtl: Natural Product Research issn: 14786419 maglogo: Y pubinfo: dt: Aug2020 vid: 34 iid: 16 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 145255021 10.1080/14786419.2018.1531403 145255021 ppf: 2315 ppct: 4 formats: tig: atl: Biological and phytochemical studies on Capparis decidua (Forssk) Edgew from Cholistan desert. aug: au: Anjum, Shazia Asif, Muhammad Zia, Kashaf Jahan, Bakhat Ashraf, Muhammad Hussain, Shafqat Qasim Hayat, Muhammad Shah, Muhammad Raza Tahir, Muhammad Nawaz affil: Cholistan Institute of Desert Studies, The Islamia University of Bahawalpur, Bahawalpur, Pakistan sug: ab: The present work deals with the biological and phytochemical studies on Capparis decidua (Forssk) Edgew from Cholistan desert of Pakistan. Aerial and floral parts of C. decidua were collected and dried under shade. Powdered materials of each part of C. decidua were extracted with methanol separately, followed by phytochemical studies. Hexane fraction of aerial parts of the C. decidua obtained after solvent-solvent extraction was purified through repeated column chromatography by increasing order of polarity. Four compounds were purified and identified as simiarenol (1), lupeol (2), taraxerol (3) and β-sitosterol (4). Simiarenol and lupeol were isolated for the first time from genus Capparis. The structures of these compounds were established by comparing the spectroscopic data (1H NMR, 13C NMR, IR, UV & Mass spectrometry) reported in literature. The structure of 1 was further confirmed by XRD analysis. Anti-bacterial activities of crude methanolic extracts were determined against 13 bacterial strains (MIC 250-1000 μg/mL). α-Glucosidase and urease inhibitory activities of pure compounds were also determined. Compounds 1, 2 and 4 showed α-glucosidase inhibition with IC50 at 96.12 ± 0.12, 65.28 ± 0.13 and 128.14 ± 0.17 μM, respectively. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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