Developmental differences in health-related quality of life in adolescent and young adult cancer survivors.
Purpose: Adolescents and young adults (AYAs) experience developmental transitions. AYA survivors of cancer are at risk for chronic health conditions due to treatment. This study examined developmental differences in AYA survivors' health-related quality of life (HRQOL) between age groups and compare...
| Publicado en: | Quality of Life Research Vol. 29; no. 9; pp. 2435 - 2445 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Sep2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=145261253&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 145261253 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09629343 GPQ jtl: Quality of Life Research issn: 09629343 maglogo: N pubinfo: dt: Sep2020 vid: 29 iid: 9 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 145261253 144004402 145261253 NLM32323061 10.1007/s11136-020-02507-4 NLM32323061 145261253 ppf: 2435 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Developmental differences in health-related quality of life in adolescent and young adult cancer survivors. aug: au: Becktell, Kerri Simpson, Pippa Phelan, Rachel Schmidt, Deb Anderson, Lynnette Nichols, Julie Bingen, Kristin affil: Department of Pediatrics, Medical College of Wisconsin, 8701 Watertown Plank Rd, MFRC3018, 53226, Milwaukee, WI, USA sug: subj: Quality of Life Psychosocial Factors Neoplasms Mortality Child Adolescence Female Adult Male Young Adult Scales Child: 6-12 years Adolescent: 13-18 years Adult: 19-44 years Female Male ab: Purpose: Adolescents and young adults (AYAs) experience developmental transitions. AYA survivors of cancer are at risk for chronic health conditions due to treatment. This study examined developmental differences in AYA survivors' health-related quality of life (HRQOL) between age groups and compared to population norms.Methods: HRQOL was assessed in AYA survivors of cancer (diagnosed before age 30) in long-term follow-up. Cancer survivors who were 12-39 years old at survey completion and completed therapy ≥ 2 years ago were included. HRQOL was assessed using the PedsQL™ and FACT.Results: Sample size was 155 survivors. PedsQL™ school functioning was worse in 15-17 year olds compared to 12-14 year olds (66.35 vs 77.60, p = 0.012). Compared to population norms, PedsQL™ outcomes were only worse in survivors' school functioning. Survivors' 18-39 years old had FACT scores that were better than population norms for overall HRQOL (91.33 vs 80.1, p < 0.001), and in physical (24.22 vs 22.7, p < 0.001), social (23.46 vs 19.1, p < 0.001), and functional well-being (22.94 vs 18.5, p < 0.001). Regression analysis identified that survivors who were < 15 years old and had not relapsed, and survivors who were 15-18 years old and had ≥ 2 late effects are at highest risk of lower HRQOL. For older survivors the highest risk group for lower HRQOL were < 21 years old at survey completion, > 7 years old at diagnosis and > 6 years post therapy.Conclusion: A trend in school functioning issues in older adolescent survivors emerged. Older survivors show improved HRQOL when compared to the general population. Those further off therapy are at risk of poor HRQOL. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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