EORTC QLU-C10D value sets for Austria, Italy, and Poland.

Objective: To develop Austrian, Italian, and Polish general population value sets for the EORTC QLU-C10D, a cancer-specific utility instrument based on the EORTC QLQ-C30, and to descriptively compare their index scores for distinct health states.Methods: The QLU-C10D descriptive system comprises 10...

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Publicado en:Quality of Life Research Vol. 29; no. 9; pp. 2485 - 2496
Autores principales: Gamper, E. M., King, M. T., Norman, R., Efficace, F., Cottone, F., Holzner, B., Kemmler, G.
Formato: research Journal Article
Publicado: Springer Nature Sep2020
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s11136-020-02536-z
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        atl: EORTC QLU-C10D value sets for Austria, Italy, and Poland.
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          Gamper, E. M.
          King, M. T.
          Norman, R.
          Efficace, F.
          Cottone, F.
          Holzner, B.
          Kemmler, G.
        affil: Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital Psychiatry II, Medical University of Innsbruck, Innsbruck, Austria
      sug:
        subj:
          Quality of Life Psychosocial Factors
          Aged, 80 and Over
          Italy
          Female
          Poland
          Cost Benefit Analysis Methods
          Male
          Aged
          Austria
          Adult
          Young Adult
          Adolescence
          Middle Age
          Human
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Questionnaires
          Aged, 80 & over
          Aged: 65+ years
          Adult: 19-44 years
          Adolescent: 13-18 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objective: To develop Austrian, Italian, and Polish general population value sets for the EORTC QLU-C10D, a cancer-specific utility instrument based on the EORTC QLQ-C30, and to descriptively compare their index scores for distinct health states.Methods: The QLU-C10D descriptive system comprises 10 health attributes and each can take on 4 levels. A standardised and pre-tested methodology has been applied for valuations including a web-based discrete choice experiment (DCE). It was administered in 1000 general population respondents per country recruited via online panels, aiming at representativeness for core socio-demographic variables.Results: In all three countries, the attributes with the largest impact on utility were physical functioning, pain, and role functioning. Cancer-specific dimensions with the largest impact were nausea and fatigue or bowel problems. Utility values of the worst health state (i.e. severe problems on all 10 dimension) were -0.111 (Austria), 0.025 (Italy), and 0.048 (Poland). Country-specific utilities differed for a selection of health states across the continuum. Austrian utilities were systematically lower for moderately and severely impaired health states.Conclusion: QLU-C10D cancer-specific utilities can now be calculated in three more countries. Differences between countries indicate that careful consideration is required when using non-country-specific value sets in economic evaluations.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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