Skeletal Muscle Mass Loss During Cancer Treatment: Differences by Race and Cancer Site.

OBJECTIVES: To examine skeletal muscle mass change in a racially diverse sample of patients undergoing cancer treatment, determine significant predictors of muscle mass loss, and explore the interaction of race and cancer site. SAMPLE & SETTING: A retrospective analysis was conducted for 212 patient...

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Publicado en:Oncology Nursing Forum Vol. 47; no. 5; pp. 557 - 567
Autores principales: Min Kyeong Jang, Chang Gi Park, Susan Hong, Laddu, Deepika, Hongjin Li, Rhee, Esther, Doorenbos, Ardith Z.
Formato: research tables/charts Journal Article
Publicado: Oncology Nursing Society Sep2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2020
      vid: 47
      iid: 5
      pid: 12496
      pub: Oncology Nursing Society
      place: Pittsburgh, Pennsylvania
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        10.1188/20.ONF.557-566
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        atl: Skeletal Muscle Mass Loss During Cancer Treatment: Differences by Race and Cancer Site.
      aug:
        au:
          Min Kyeong Jang
          Chang Gi Park
          Susan Hong
          Laddu, Deepika
          Hongjin Li
          Rhee, Esther
          Doorenbos, Ardith Z.
        affil: Postdoctoral fellow in the Cancer Center and in the College of Nursing, University of Illinois at Chicago
      sug:
        subj:
          Neoplasms Drug Therapy
          Chemotherapy, Cancer Adverse Effects
          Sarcopenia Chemically Induced
          Muscle, Skeletal Pathology
          Sarcopenia Risk Factors
          Risk Assessment
          Race Factors
          Neoplasms by Site
          Human
          Retrospective Design
          Record Review
          Cancer Patients
          Academic Medical Centers
          Tomography, X-Ray Computed
          Descriptive Statistics
          Rectal Neoplasms Complications
          Black Persons
          Male
          Female
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Illinois
          Paired T-Tests
          Multiple Linear Regression
          Data Analysis Software
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: OBJECTIVES: To examine skeletal muscle mass change in a racially diverse sample of patients undergoing cancer treatment, determine significant predictors of muscle mass loss, and explore the interaction of race and cancer site. SAMPLE & SETTING: A retrospective analysis was conducted for 212 patients seeking treatment at a university hospital clinic. METHODS & VARIABLES: Skeletal muscle mass index (SMI) was determined by computed tomography at the time of cancer diagnosis and with cancer treatment. RESULTS: One hundred thirty-four patients (63%) had SMI loss with cancer treatment. Race and cancer site were found to be significant predictors of SMI loss. Compared to other racial groups, non-Hispanic Black (NHB) patients had the greatest SMI loss (p < 0.001) with cancer treatment. NHB patients with rectal cancer experienced the greatest SMI loss compared to patients of other races and cancer types. IMPLICATIONS FOR NURSING: To improve survivorship care for patients with cancer, it is essential to develop strategies for assessing and managing skeletal muscle mass loss throughout treatment, particularly for NHB patients with rectal cancer.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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