A systematic review of the impact of contemporary treatment modalities for cervical cancer on women's self-reported health-related quality of life.
Purpose: Given the high survival rate of cervical cancer patients, understanding women's health-related quality of life (HRQL) during and after treatment is of major clinical importance. We conducted a systematic review to synthesize all available evidence about the effects of each contemporary trea...
| Publicado en: | Supportive Care in Cancer Vol. 28; no. 10; pp. 4627 - 4645 |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Springer Nature
Oct2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=145302010&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 145302010 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09414355 O1J jtl: Supportive Care in Cancer issn: 09414355 maglogo: N pubinfo: dt: Oct2020 vid: 28 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 145302010 144445330 145302010 NLM32556622 145302010 10.1007/s00520-020-05554-2 NLM32556622 145302010 ppf: 4627 ppct: 18 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: A systematic review of the impact of contemporary treatment modalities for cervical cancer on women's self-reported health-related quality of life. aug: au: Wiltink, L. M. King, M. Müller, F. Sousa, M. S. Tang, M. Pendlebury, A. Pittman, J. Roberts, N. Mileshkin, L. Mercieca-Bebber, R. Tait, M.-A. Campbell, R. Rutherford, C. affil: The University of Sydney, Faculty of Science, School of Psychology, Quality of Life Office, Sydney, Australia sug: subj: Quality of Life Psychosocial Factors Cervix Neoplasms Therapy Female Self Report Cervix Neoplasms Pathology Human Scales Female ab: Purpose: Given the high survival rate of cervical cancer patients, understanding women's health-related quality of life (HRQL) during and after treatment is of major clinical importance. We conducted a systematic review to synthesize all available evidence about the effects of each contemporary treatment modality for cervical cancer on all dimensions of women's HRQL, including symptoms, functioning, and global HRQL.Methods: We searched four electronic databases from January 2000 to September 2019, cross-referenced and searched by author name for studies of patients treated for cervical cancer that reported patient-reported outcomes (PROs) before treatment and with at least one post-treatment measurement. Two independent reviewers applied inclusion and quality criteria and extracted findings. Studies were categorized by treatment to determine specific treatment effects on PROs. Results were narratively summarized.Results: We found twenty-nine papers reporting 23 studies. After treatments with curative intent for early or locally advanced disease, lymphedema, diarrhea, menopausal symptoms, tight and shorter vagina, pain during intercourse, and sexual worries remained long-term problems; however, sexual activity improved over time. HRQL and psychological distress were impacted during treatment with also worsening of global HRQL but improved 3-6 months after treatment. In patients with metastatic or recurrent disease, pain improved during palliative treatment or remained stable, with no differences in global HRQL found over time.Conclusion: Whereas most symptoms worsen during treatment and improve in the first 3 months after completing treatment, symptoms like lymphedema, menopausal symptoms, and sexual worries develop gradually and persist after curative treatment. These findings can be used to inform clinical practice and facilitate communication and shared decision-making. More research is needed in very early cervical cancer and the impact of fertility sparing therapy on PROs. pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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