Effects of caffeine on reaction time are mediated by attentional rather than motor processes.
Background Caffeine has a well-established effect on reaction times (RTs) but the neurocognitive mechanisms underlying this are unclear. Methods In the present study, 15 female participants performed an oddball task after ingesting caffeine or a placebo, and electroencephalographic data were obtaine...
| Publicado en: | Psychopharmacology Vol. 235; no. 3; pp. 749 - 760 |
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| Autores principales: | , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Mar2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=145328754&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 145328754 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00333158 EJD jtl: Psychopharmacology issn: 00333158 maglogo: N pubinfo: dt: Mar2018 vid: 235 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 145328754 10.1007/s00213-017-4790-7 145328754 ppf: 749 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Effects of caffeine on reaction time are mediated by attentional rather than motor processes. aug: au: Saville, Christopher W. N. de Morree, H. M. Dundon, Neil M. Marcora, S. M. Klein, C. affil: North Wales Clinical Psychology Programme, School of Psychology, Bangor University, Adeilad Brigantia, Ffordd Penrallt, Bangor, Gwynedd, Wales LL57 2AS, UK. sug: ab: Background Caffeine has a well-established effect on reaction times (RTs) but the neurocognitive mechanisms underlying this are unclear. Methods In the present study, 15 female participants performed an oddball task after ingesting caffeine or a placebo, and electroencephalographic data were obtained. Single-trial P3b latencies locked to the stimulus and to the response were extracted and mediation models were fitted to the data to test whether caffeine’s effect on RTs was mediated by its effect on either type of P3b latencies. Results Stimulus-locked latencies showed clear evidence of mediation, with approximately a third of the effect of caffeine on RTs running through the processes measured by stimulus-locked latencies. Caffeine did not affect response-locked latencies, so could not mediate the effect. Discussion These findings are consistent with caffeine’s effect on RTs being a result of its effect on perceptual-attentional processes, rather than motor processes. The study is the first to apply mediation analysis to single-trial P3b data and this technique holds promise for mental chronometric studies into the effects of psychopharmacological agents. The R code for performing the single trial analysis and mediation analysis are included as supplementary materials. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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