Implementation science outcomes of a gender-focused HIV and alcohol risk-reduction intervention in usual-care settings in South Africa.

Background: South Africa has the highest HIV prevalence globally, which disproportionately affects women. Hazardous alcohol use reduces antiretroviral adherence which can lead to adverse health. Few evidence-based interventions addressing hazardous alcohol use and HIV have been implemented in real-w...

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Publicado en:Drug & Alcohol Dependence Vol. 213; pp. 108206 - 108207
Autores principales: Gichane, Margaret W, Wechsberg, Wendee M, Ndirangu, Jacqueline, Browne, Felicia A, Bonner, Courtney Peasant, Grimwood, Ashraf, Shaikh, Najma, Howard, Brittni, Zule, William A
Formato: research Journal Article
Publicado: Elsevier B.V. Aug2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2020
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      pub: Elsevier B.V.
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        10.1016/j.drugalcdep.2020.108206
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        atl: Implementation science outcomes of a gender-focused HIV and alcohol risk-reduction intervention in usual-care settings in South Africa.
      aug:
        au:
          Gichane, Margaret W
          Wechsberg, Wendee M
          Ndirangu, Jacqueline
          Browne, Felicia A
          Bonner, Courtney Peasant
          Grimwood, Ashraf
          Shaikh, Najma
          Howard, Brittni
          Zule, William A
        affil: RTI International, 3040 E. Cornwallis Road, Research Triangle Park, NC, 27709, USA
      sug:
        subj:
          Adult
          Female
          HIV Infections Epidemiology
          Stigma
          Behavior
          Ethanol
          South Africa
          Alcohol Drinking
          Male
          Women's Health
          Funding Source
          Adult: 19-44 years
          Female
          Male
      ab: Background: South Africa has the highest HIV prevalence globally, which disproportionately affects women. Hazardous alcohol use reduces antiretroviral adherence which can lead to adverse health. Few evidence-based interventions addressing hazardous alcohol use and HIV have been implemented in real-world settings. This study aimed to evaluate implementation outcomes from the Women's Health CoOp (WHC)-an evidence-based gender-focused HIV intervention-which was implemented in Cape Town.Methods: We conducted this implementation science trial using a modified stepped-wedge design. Four health clinics were paired with four substance use rehabilitation programs and randomized into four cycles. Women living with HIV and who use alcohol or other drugs were recruited into each cycle (n = 120 each cycle). We assessed adoption, acceptability, appropriateness, cost, and fidelity using a mixed methods approach.Results: Adoption: 100 % of staff trained in the WHC and designated as interventionists delivered one or more workshops. Acceptability: Interventionists found the WHC content beneficial to their patients and the WHC improved connections between clinical units in facilities. Appropriateness: The WHC aligned with facility goals to improve antiretroviral adherence and reduce alcohol use; however, there were implementation challenges, including staff shortages, stigma, and few places to refer women for supportive services. Cost: The cost of implementing the WHC was 20.59 ZAR (1.40 USD) per attendee. Fidelity: Interventionists implemented the WHC with high fidelity and quality.Conclusions: The findings suggest it is feasible to integrate the WHC into usual-care settings. Future efforts to scale up the intervention will need to address social and structural implementation challenges.Trial Registration: NCT02733003 approved 1/21/2016.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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