Increased tortuosity of basilar artery might be associated with higher risk of aneurysm development.
Objectives: We analysed tortuosity of basilar artery (BA) to determine its relationship with the presence of aneurysm.Methods: We retrospectively analysed 71 patients with BA aneurysms along with 71 age- and risk factors-matched control patients without BA aneurysm. From patients' medical records, w...
| Publicado en: | European Radiology Vol. 30; no. 10; pp. 5625 - 5633 |
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| Autores principales: | , , , , , , , , |
| Formato: | diagnostic images equations & formulas research tables/charts Journal Article |
| Publicado: |
Springer Nature
Oct2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=145536756&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 145536756 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Oct2020 vid: 30 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 145536756 144017602 145536756 NLM32405752 145536756 10.1007/s00330-020-06917-3 NLM32405752 145536756 ppf: 5625 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Increased tortuosity of basilar artery might be associated with higher risk of aneurysm development. aug: au: Kliś, Kornelia M. Krzyżewski, Roger M. Kwinta, Borys M. Łasocha, Bartłomiej Brzegowy, Paweł Stachura, Krzysztof Popiela, Tadeusz J. Borek, Radosław Gąsowski, Jerzy affil: Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland sug: subj: Basilar Artery Anatomy and Histology Cerebral Aneurysm Etiology Basilar Artery Physiopathology Male Regression Adult Cerebral Angiography Female Middle Age Cerebral Aneurysm Physiopathology Retrospective Design Hospitalization Aged Risk Factors Funding Source Human Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Objectives: We analysed tortuosity of basilar artery (BA) to determine its relationship with the presence of aneurysm.Methods: We retrospectively analysed 71 patients with BA aneurysms along with 71 age- and risk factors-matched control patients without BA aneurysm. From patients' medical records, we obtained their history including previous and current diseases and medications. For each patient, we calculated relative length (RL), sum of angle metrics (SOAM), triangular index (TI), product of angle distance (PAD) and inflexion count metrics (ICM). We used t-test and Mann-Whitney U test for continuous variables and χ2 test for dichotomised variables. To find independent predictors of BA aneurysm, we employed logistic regression analysis.Results: We found significant positive correlation between age and SOAM (R = 0.195, p = 0.02) and PAD (R = 0.199, p = 0.018). Our study also showed that patients with BA aneurysm had significantly higher SOAM (0.21 ± 0.16 vs. 0.11 ± 0.08; p < 0.01), PAD (0.30 ± 0.19 vs. 0.18 ± 0.11; p < 0.01), TI (0.23 ± 0.23 vs. 0.10 ± 0.16; p < 0.01) and ICM (0.20 ± 0.16 vs. 0.15 ± 0.11; p = 0.045). In multivariate logistic regression analysis, after adjustment for all possible confounders, SOAM (OR = 1.086; 95% CI 1.046-1.136; p < 0.01) and TI (OR = 1.004; 95%C: 1.002-1.006; p < 0.01) remained independently associated with higher risk of BA aneurysm.Conclusions: Increased tortuosity of BA is associated with higher risk of its aneurysm development.Key Points: • Basilar artery sum of angle metrics and product of angle distance are correlated with age. • Basilar artery tortuosity is independently associated with higher risk of its aneurysm development. • Basilar artery tortuosity is positively correlated with its diameter and bifurcation angle. pubtype: Academic Journal doctype: diagnostic images equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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