Urothelial Carcinoma Detection Based on Copy Number Profiles of Urinary Cell-Free DNA by Shallow Whole-Genome Sequencing.

Current noninvasive assays for urothelial carcinoma (UC) lack clinical sensitivity and specificity. Given the utility of plasma cell-free DNA (cfDNA) biomarkers, the development of urinary cfDNA biomarkers may improve the diagnostic sensitivity. METHODS: We assessed copy number alterations (CNAs) by...

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Publicado en:	Clinical Chemistry Vol. 66; no. 1; pp. 188 - 199
Autores principales:	Guangzhe Ge, Ding Peng, Bao Guan, Yuanyuan Zhou, Yanqing Gong, Yue Shi, Xueyu Hao, Zhengzheng Xu, Jie Qi, Huan Lu, Xiaoyun Zhang, Yonghao Zhan, Yifan Li, Yucai Wu, Guangpu Ding, Qi Shen, Qun He, Xuesong Li, Liqun Zhou, Weimin Ci
Formato:	Journal Article
Publicado:	Oxford University Press / USA Jan2020
Acceso en línea:	Ver este registro en EBSCOhost