Long-distance disorder-disorder relation extraction with bootstrapped noisy data.
Objective: Artificial intelligence in healthcare increasingly relies on relations in knowledge graphs for algorithm development. However, many important relations are not well covered in existing knowledge graphs. We aim to develop a novel long-distance relation extraction algorithm that leverages t...
| Publicado en: | Journal of Biomedical Informatics Vol. 109 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Academic Press Inc.
Sep2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=145995889&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 145995889 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15320464 OMB jtl: Journal of Biomedical Informatics issn: 15320464 maglogo: N pubinfo: dt: Sep2020 vid: 109 pid: 735 pub: Academic Press Inc. place: Burlington, Massachusetts artinfo: ui: 145995889 145995889 NLM32771539 145995889 10.1016/j.jbi.2020.103529 NLM32771539 145995889 ppct: 1 formats: tig: atl: Long-distance disorder-disorder relation extraction with bootstrapped noisy data. aug: au: Lin, Yucong Li, Yang Lu, Keming Ma, Cheng Zhao, Peng Gao, Daiqi Fan, Zihao Cheng, Zijie Wang, Zheyu Yu, Sheng affil: Center for Statistical Science, Tsinghua University, Beijing, Beijing, China sug: subj: Human ab: Objective: Artificial intelligence in healthcare increasingly relies on relations in knowledge graphs for algorithm development. However, many important relations are not well covered in existing knowledge graphs. We aim to develop a novel long-distance relation extraction algorithm that leverages the article section structure and is trained with bootstrapped noisy data to identify important relations for diagnosis, including may cause, may be caused by, and differential diagnosis.Methods: Known relations were extracted from semistructured web pages and a relational database and were paired with sentences containing corresponding medical concepts to form training data. The sentence form was extended to allow one concept to be in the title. An attention mechanism was applied to reduce the effect of noisily labeled sentences. Section structure embedding was added to provide additional context for relation expressions. Graph information was further incorporated into the model to differentiate the target relations whose expressions were often similar and interwoven.Results: The extended sentence form allowed 1.75 times as many relations and 2.17 times as many sentences to be found compared to the conventional form. The various components of the proposed model all added to the accuracy. Overall, the positive sample accuracy of the proposed model was 9 percentage points higher than baseline deep learning models and 13 percentage points higher than naïve Bayes and support vector machines.Conclusion: Our bootstrap data preparation method and the extended sentence form could form a large training dataset to enable algorithm development and data mining efforts. Section structure embedding and graph information significantly increased prediction accuracy. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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