Unlocking the PACS DICOM Domain for its Use in Clinical Research Data Warehouses.

Clinical Data Warehouses (DWHs) are used to provide researchers with simplified access to pseudonymized and homogenized clinical routine data from multiple primary systems. Experience with the integration of imaging and metadata from picture archiving and communication systems (PACS), however, is ra...

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Publicado en:Journal of Digital Imaging Vol. 33; no. 4; pp. 1016 - 1026
Autores principales: Kaspar, Mathias, Liman, Leon, Ertl, Maximilian, Fette, Georg, Seidlmayer, Lea Katharina, Schreiber, Laura, Puppe, Frank, Störk, Stefan
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Springer Nature Aug2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2020
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-020-00334-0
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        atl: Unlocking the PACS DICOM Domain for its Use in Clinical Research Data Warehouses.
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          Kaspar, Mathias
          Liman, Leon
          Ertl, Maximilian
          Fette, Georg
          Seidlmayer, Lea Katharina
          Schreiber, Laura
          Puppe, Frank
          Störk, Stefan
        affil: Comprehensive Heart Failure Center and Department of Internal Medicine I, Würzburg University Hospital, Würzburg, Germany
      sug:
        subj:
          Picture Archiving and Communication Systems
          Clinical Research
          Data Warehouse
          Diagnostic Imaging
          Systems Integration
          Downloading (Database)
          Human
          Data Analytics
          Descriptive Statistics
          World Wide Web
          Computing Methodologies
      ab: Clinical Data Warehouses (DWHs) are used to provide researchers with simplified access to pseudonymized and homogenized clinical routine data from multiple primary systems. Experience with the integration of imaging and metadata from picture archiving and communication systems (PACS), however, is rare. Our goal was therefore to analyze the viability of integrating a production PACS with a research DWH to enable DWH queries combining clinical and medical imaging metadata and to enable the DWH to display and download images ad hoc. We developed an application interface that enables to query the production PACS of a large hospital from a clinical research DWH containing pseudonymized data. We evaluated the performance of bulk extracting metadata from the PACS to the DWH and the performance of retrieving images ad hoc from the PACS for display and download within the DWH. We integrated the system into the query interface of our DWH and used it successfully in four use cases. The bulk extraction of imaging metadata required a median (quartiles) time of 0.09 (0.03–2.25) to 12.52 (4.11–37.30) seconds for a median (quartiles) number of 10 (3–29) to 103 (8–693) images per patient, depending on the extraction approach. The ad hoc image retrieval from the PACS required a median (quartiles) of 2.57 (2.57–2.79) seconds per image for the download, but 5.55 (4.91–6.06) seconds to display the first and 40.77 (38.60–41.63) seconds to display all images using the pure web-based viewer. A full integration of a production PACS with a research DWH is viable and enables various use cases in research. While the extraction of basic metadata from all images can be done with reasonable effort, the extraction of all metadata seems to be more appropriate for subgroups.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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