Chronic minocycline treatment exerts antidepressant effect, inhibits neuroinflammation, and modulates gut microbiota in mice.

Rational: Minocycline is a second-generation, semi-synthetic tetracycline, and has broad spectrum-antibacterial activity. Interestingly, many studies have demonstrated that minocycline is beneficial for depression, which may be due to its effects on neuroinflammation modulation. Recently, gut microb...

Full description

Bibliographic Details

Published in:	Psychopharmacology Vol. 237; no. 10; pp. 3201 - 3214
Main Authors:	Yang, Qi, Luo, Li, Sun, Ting, Yang, Le, Cheng, Li-Fei, Wang, Yan, Liu, Qing-Qing, Liu, An, Liu, Hai-Yan, Zhao, Ming-Gao, Wu, Sheng-Xi, Feng, Bin
Format:	Journal Article
Published:	Springer Nature Oct2020
Online Access:	View this record in EBSCOhost