Model‐Based Evaluation of Linear Limited and Bayesian Sparse Sampling for Therapeutic Monitoring of Recombinant Coagulation Factor IX.
Dosing of coagulation factor products is mainly determined based on a patient's body weight; however, several studies have reported high interindividual variability in their pharmacokinetics (PK). The objective of this study was to develop and evaluate 2 sparse sampling methods for the estimation of...
| Published in: | Journal of Clinical Pharmacology Vol. 60; no. 11; pp. 1453 - 1461 |
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| Main Authors: | , |
| Format: | equations & formulas research tables/charts Journal Article |
| Published: |
Wiley-Blackwell
Nov2020
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| Online Access: | View this record in EBSCOhost |