The rate of dasotraline brain entry is slow following intravenous administration.

Rationale: Drugs that rapidly increase dopamine levels have an increased risk of abuse. Dasotraline (DAS) is a dopamine and norepinephrine reuptake inhibitor characterized by slow oral absorption with low potential for abuse. However, it remains unclear whether intravenous (i.v.) administration woul...

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Bibliographic Details

Published in:	Psychopharmacology Vol. 237; no. 11; pp. 3435 - 3447
Main Authors:	Lew, Robert, Constantinescu, Cristian C., Holden, Daniel, Carson, Richard E., Carroll, Vincent, Galluppi, Gerald, Koblan, Kenneth S., Hopkins, Seth C.
Format:	Journal Article
Published:	Springer Nature Nov2020
Online Access:	View this record in EBSCOhost