Time‐ and frequency‐domain analysis of repolarization phase during recovery from exercise in healthy subjects.

Background/aim: Recently, data from temporal dispersion of myocardial repolarization analysis have gained a capital role in the sudden cardiac death risk stratification. Aim of this study was to evaluate the influence of heart rate, autonomic nervous system, and controlled breathing on different myo...

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Publicado en:Pacing & Clinical Electrophysiology Vol. 43; no. 10; pp. 1096 - 1104
Autores principales: Piccirillo, Gianfranco, Moscucci, Federica, Iorio, Claudia Di, Fabietti, Marcella, Mastropietri, Fabiola, Crapanzano, Davide, Bertani, Gaetano, Sabatino, Teresa, Zaccagnini, Giulia, Lospinuso, Ilaria, Magrì, Damiano
Formato: equations & formulas research tables/charts tracings Journal Article
Publicado: Wiley-Blackwell Oct2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2020
      vid: 43
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/pace.14038
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        atl: Time‐ and frequency‐domain analysis of repolarization phase during recovery from exercise in healthy subjects.
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        au:
          Piccirillo, Gianfranco
          Moscucci, Federica
          Iorio, Claudia Di
          Fabietti, Marcella
          Mastropietri, Fabiola
          Crapanzano, Davide
          Bertani, Gaetano
          Sabatino, Teresa
          Zaccagnini, Giulia
          Lospinuso, Ilaria
          Magrì, Damiano
        affil: Dipartimento di Scienze Cliniche, Internistiche, Anestesiologiche e Cardiovascolari, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy
      sug:
        subj:
          Recovery, Exercise
          Electrocardiography
          Heart Conduction System Physiology
          Myocardium Physiology
          Human
          Volunteer Workers
          Exercise Physiology
          Heart Rate Evaluation
          Sympathetic Nervous System Physiology
          Descriptive Statistics
      ab: Background/aim: Recently, data from temporal dispersion of myocardial repolarization analysis have gained a capital role in the sudden cardiac death risk stratification. Aim of this study was to evaluate the influence of heart rate, autonomic nervous system, and controlled breathing on different myocardial repolarization markers in healthy subjects. Method: Myocardial repolarization dispersion markers from short‐period (5 minutes) electrocardiogram (ECG) analysis (time and frequency domain) have been obtained in 21 healthy volunteers during the following conditions: free breathing (rest); controlled breathing (resp); the first 5 minutes of postexercise recovery phases (exercisePeak), maximum sympathetic activation; and during the second 5 minutes of postexercise recovery phases (exerciseRecovery), intermediate sympathetic activation. Finally, we analyzed the whole repolarization (QTe), the QT peak (QTp), and T peak ‐ T end intervals (Te). Results: During the exercisePeak, major part of repolarization variables changed in comparison to the rest and resp conditions. Particularly, QTe, QTp, and Te standard deviations (QTeSD, QTpSD, and TeSD); variability indexes (QTeVI and QTpVI), normalized variances (QTeVN, QTpVN, and TeVN); and the ratio between short‐term QTe, QTp, and Te variability RR (STVQTe/RR, STVQTp/RR, and STVTe/RR) increased. During exerciseRecovery, QTpSD (P <.05), QTpVI (P <.05), QTeVN (P <.05), QTpVN (P <.001), TeVN (P <.05), STVQTe/RR (P <.05), STVQTp/RR (P <.001), and STVTe/RR (P <.001) were significantly higher in comparison to the rest. The slope between QTe (0.24 ± 0.06) or QTp (0.17 ± 0.06) and RR were significantly higher than Te (0.07 ± 0.06, P <.001). Conclusion: Heart rate and sympathetic activity, obtained during exercise, seem able to influence the time domain markers of myocardial repolarization dispersion in healthy subjects, whereas they do not alter any spectral components.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        tracings
        Journal Article
      ougenre: Article
    language: English
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