Diagnostic Efficiency of the Breast Ultrasound Computer-Aided Prediction Model Based on Convolutional Neural Network in Breast Cancer.

This study aimed to construct a breast ultrasound computer-aided prediction model based on the convolutional neural network (CNN) and investigate its diagnostic efficiency in breast cancer. A retrospective analysis was carried out, including 5000 breast ultrasound images (benign: 2500; malignant: 25...

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Publicado en:Journal of Digital Imaging Vol. 33; no. 5; pp. 1218 - 1224
Autores principales: Zhang, Heqing, Han, Lin, Chen, Ke, Peng, Yulan, Lin, Jiangli
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Oct2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2020
      vid: 33
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-020-00357-7
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        atl: Diagnostic Efficiency of the Breast Ultrasound Computer-Aided Prediction Model Based on Convolutional Neural Network in Breast Cancer.
      aug:
        au:
          Zhang, Heqing
          Han, Lin
          Chen, Ke
          Peng, Yulan
          Lin, Jiangli
        affil: Department of Ultrasound, West China Hospital, Sichuan University, Chengdu, China
      sug:
        subj:
          Breast Neoplasms Ultrasonography
          Neural Networks (Computer)
          Prediction Models
          Computers and Computerization
          Sensitivity and Specificity
          Human
          Retrospective Design
          ROC Curve
          Ultrasound Technologists
          Descriptive Statistics
          Validity
      ab: This study aimed to construct a breast ultrasound computer-aided prediction model based on the convolutional neural network (CNN) and investigate its diagnostic efficiency in breast cancer. A retrospective analysis was carried out, including 5000 breast ultrasound images (benign: 2500; malignant: 2500) as the training group. Different prediction models were constructed using CNN (based on InceptionV3, VGG16, ResNet50, and VGG19). Additionally, the constructed prediction models were tested using 1007 images of the test group (benign: 788; malignant: 219). The receiver operating characteristic curves were drawn, and the corresponding areas under the curve (AUCs) were obtained. The model with the highest AUC was selected, and its diagnostic accuracy was compared with that obtained by sonographers who performed and interpreted ultrasonographic examinations using 683 images of the comparison group (benign: 493; malignant: 190). In the model test with the test group images, the AUCs of the constructed InceptionV3, VGG16, ResNet50, and VGG19 models were 0.905, 0.866, 0.851, and 0.847, respectively. The InceptionV3 model showed the largest AUC, with statistically significant differences compared with the other models (P < 0.05). In the classification of the comparison group images, the AUC (0.913) of the InceptionV3 model was larger than that (0.846) obtained by sonographers, showing a statistically significant difference (P < 0.05). The breast ultrasound computer-aided prediction model based on CNN showed high accuracy in the prediction of breast cancer.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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