Joint Diabetic Macular Edema Segmentation and Characterization in OCT Images.

The automatic identification and segmentation of edemas associated with diabetic macular edema (DME) constitutes a crucial ophthalmological issue as they provide useful information for the evaluation of the disease severity. According to clinical knowledge, the DME disorder can be categorized into t...

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Publicado en:Journal of Digital Imaging Vol. 33; no. 5; pp. 1335 - 1352
Autores principales: de Moura, Joaquim, Samagaio, Gabriela, Novo, Jorge, Almuina, Pablo, Fernández, María Isabel, Ortega, Marcos
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Oct2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2020
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      pub: Springer Nature
      place: New York, New York
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        atl: Joint Diabetic Macular Edema Segmentation and Characterization in OCT Images.
      aug:
        au:
          de Moura, Joaquim
          Samagaio, Gabriela
          Novo, Jorge
          Almuina, Pablo
          Fernández, María Isabel
          Ortega, Marcos
        affil: Department of Computer Science and Information Technology, University of A Coruña, 15071, A Coruña, Spain
      sug:
        subj:
          Tomography, Optical Coherence
          Diabetic Retinopathy Diagnosis
          Macular Edema Diagnosis
          Human
          Severity of Illness
          Retinal Detachment
          Quality of Life
      ab: The automatic identification and segmentation of edemas associated with diabetic macular edema (DME) constitutes a crucial ophthalmological issue as they provide useful information for the evaluation of the disease severity. According to clinical knowledge, the DME disorder can be categorized into three main pathological types: serous retinal detachment (SRD), cystoid macular edema (CME), and diffuse retinal thickening (DRT). The implementation of computational systems for their automatic extraction and characterization may help the clinicians in their daily clinical practice, adjusting the diagnosis and therapies and consequently the life quality of the patients. In this context, this paper proposes a fully automatic system for the identification, segmentation and characterization of the three ME types using optical coherence tomography (OCT) images. In the case of SRD and CME edemas, different approaches were implemented adapting graph cuts and active contours for their identification and precise delimitation. In the case of the DRT edemas, given their fuzzy regional appearance that requires a complex extraction process, an exhaustive analysis using a learning strategy was designed, exploiting intensity, texture, and clinical-based information. The different steps of this methodology were validated with a heterogeneous set of 262 OCT images, using the manual labeling provided by an expert clinician. In general terms, the system provided satisfactory results, reaching Dice coefficient scores of 0.8768, 0.7475, and 0.8913 for the segmentation of SRD, CME, and DRT edemas, respectively.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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