Efficacy of Rituximab for Refractory Pyoderma Gangrenosum-Like Ulcers in Granulomatosis With Polyangiitis Associated to Antiphospholipid Antibodies.

Pyoderma gangrenosum (PG) is a neutrophilic dermatosis that most often presents with painful ulcerations of violaceous borders in lower limbs and/or trunk. PG treatment varies according to the severity of the lesion and may either respond to local therapies or require immunosuppressive agents. In th...

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Publicado en:Archives of Rheumatology Vol. 35; no. 3; pp. 449 - 454
Autores principales: RIERA, Julia, MUSURUANA, Jorge, COSTA, Cecilia, CAVALLASCA, Javier
Formato: case study pictorial tables/charts Journal Article
Publicado: Aves Yayincilik A.S. Sep2020
Acceso en línea:Ver este registro en EBSCOhost
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        10.46497/ArchRheumatol.2020.7498
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        atl: Efficacy of Rituximab for Refractory Pyoderma Gangrenosum-Like Ulcers in Granulomatosis With Polyangiitis Associated to Antiphospholipid Antibodies.
      aug:
        au:
          RIERA, Julia
          MUSURUANA, Jorge
          COSTA, Cecilia
          CAVALLASCA, Javier
        affil: Hospital JB Iturraspe, Rheumatology and Autoimmune Diseases, Santa Fe, Argentina
      sug:
        subj:
          Pyoderma Gangrenosum Drug Therapy
          Rituximab Therapeutic Use
          Vasculitis
          Female
          Middle Age
          Immunosuppressive Agents
          Antibodies
          Microscopic Polyangiitis
          Middle Aged: 45-64 years
          Female
      ab: Pyoderma gangrenosum (PG) is a neutrophilic dermatosis that most often presents with painful ulcerations of violaceous borders in lower limbs and/or trunk. PG treatment varies according to the severity of the lesion and may either respond to local therapies or require immunosuppressive agents. In this article, we present the case of an antiphospholipid antibody-positive 59-year-old female patient diagnosed with granulomatosis with polyangiitis who developed severe PG-like skin involvement that was responsive to rituximab therapy.
      pubtype: Academic Journal
      doctype:
        case study
        pictorial
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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