Four Pistacia atlantica subspecies (atlantica, cabulica, kurdica and mutica): A review of their botany, ethnobotany, phytochemistry and pharmacology.

Pistacia atlantica (wild pistachio) belongs to the Anacardiaceae family, and growing from the Mediterranean basin to central Asia, especially in Iran, Turkey, Iraq and Saudi Arabia where it is extensively used in traditional medicine for a wide range of ailments related to relieving upper abdominal...

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Publicado en:Journal of Ethnopharmacology Vol. 265
Autores principales: Ben Ahmed, Ziyad, Yousfi, Mohamed, Viaene, Johan, Dejaegher, Bieke, Demeyer, Kristiaan, Heyden, Yvan Vander
Formato: review tables/charts Journal Article
Publicado: Elsevier B.V. Jan2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2021
      vid: 265
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      pub: Elsevier B.V.
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        10.1016/j.jep.2020.113329
        146751713
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        atl: Four Pistacia atlantica subspecies (atlantica, cabulica, kurdica and mutica): A review of their botany, ethnobotany, phytochemistry and pharmacology.
      aug:
        au:
          Ben Ahmed, Ziyad
          Yousfi, Mohamed
          Viaene, Johan
          Dejaegher, Bieke
          Demeyer, Kristiaan
          Heyden, Yvan Vander
        affil: Laboratory of Science Fundamental University Amar Telidji, BP37G, Laghouat, Algeria
      sug:
        subj:
          Plants, Medicinal Analysis
          Plant Extracts Analysis
          Medicine, Traditional
          Drug Evaluation
          Antiinfective Agents
          Antifungal Agents
          Antiinflammatory Agents
          Analgesics
          Antineoplastic Agents
          Cholinesterase Inhibitors
          Hypoglycemic Agents
          Urease Antagonists and Inhibitors
          Antihypertensive Agents
          Antifibrinolytic Agents
      ab: Pistacia atlantica (wild pistachio) belongs to the Anacardiaceae family, and growing from the Mediterranean basin to central Asia, especially in Iran, Turkey, Iraq and Saudi Arabia where it is extensively used in traditional medicine for a wide range of ailments related to relieving upper abdominal discomfort and pain, dyspepsia and peptic ulcer. Despite the diverse biological activities of P. atlantica , there is no current review summarizing medicinal properties of its subspecies, including cabulica , kurdica and mutica. Thus, this paper aims to explore the current understanding of the chemical, pharmacological, and biochemical properties of the extracts and the main active constituents found in each subspecies of this plant. Peer-reviewed articles, using " Pistacia atlantica " as search term (″all fields″), were retrieved from Scifinder, Pubmed, Science direct, Wiley, Springer, ACS, Scielo, Web of Science and other web search instruments (Google Scholar, Yahoo search). Papers published until July 2020 are considered. In addition, various books were consulted that contained botanical and ethnopharmacological information. The information provided in this review is based on peer-reviewed papers in English and French. Phytochemical studies have shown the presence of numerous valuable compounds, including volatile compounds, flavonoids, phenolic compounds, fatty acids, tocopherols and phytosterols. P. atlantica contains also minerals and trace elements, like iron, lead, copper, potassium, sodium and calcium; fatty acids, like oleic, linoleic, and palmitic acid; fat-soluble vitamins, such as α, β, γ and δ tocopherols; phytosterols, like betasitosterol, stigmasterol, campesterol and Δ5-avenasterol. Crude extracts and isolated compounds from P. atlantica show a wide range of pharmacological properties, such as antimicrobial, antifungal, anti-inflammatory, analgesic, antinociceptive, wound healing, anticancer, cytotoxic, anticholinesterase, antidiabetic, hepatoprotective, urease inhibition, antihypertension, nipple fissure healing, antileishmanial and antiplasmodial activities. However, there are no reports summarizing the P. atlantica bioactivity, its therapeutic value, and the roles played by each of the numerous phytoconstituents. Many traditional uses of P. atlantica and its subspecies have now been confirmed by pharmacologic research. Systematic phytochemical investigation of the P. atlantica subspecies and the pharmacological properties, especially the mechanisms of action and toxicology, to illustrate their ethnomedicinal use, to explore the therapeutic potential and support further health-care product development, will undoubtedly be the focus of further research. Therefore, detailed and extensive studies and clinical evaluation of P. atlantica subspecies should be carried out in future for the safety approval of therapeutic applications. Image 1 • Comprehensive literature overview on P. atlantica. • Phytochemical analysis: discussion of various herbal compounds. • Pharmacological information in relation to diverse activities. • Clinical trials.
      pubtype: Academic Journal
      doctype:
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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