Application of Artificial Intelligence Techniques for the Estimation of Basal Insulin in Patients with Type I Diabetes.

Artificial intelligence techniques have been positioned in the resolution of problems in various areas of healthcare. Clinical decision support systems developed from this technology have optimized the healthcare of patients with chronic diseases through mobile applications. In this study, several m...

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Publicado en:International Journal of Endocrinology pp. 1 - 9
Autores principales: Guzman Gómez, Guillermo Edinson, Burbano Agredo, Luis Eduardo, Martínez, Veline, Bedoya Leiva, Oscar Fernando
Formato: Journal Article
Publicado: Wiley-Blackwell 11/3/2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 11/3/2020
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        146805301
        10.1155/2020/7326073
        146805301
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        atl: Application of Artificial Intelligence Techniques for the Estimation of Basal Insulin in Patients with Type I Diabetes.
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        au:
          Guzman Gómez, Guillermo Edinson
          Burbano Agredo, Luis Eduardo
          Martínez, Veline
          Bedoya Leiva, Oscar Fernando
        affil: Fundación Valle del Lili, Departamento de Endocrinología, Cali, Colombia
      sug:
      ab: Artificial intelligence techniques have been positioned in the resolution of problems in various areas of healthcare. Clinical decision support systems developed from this technology have optimized the healthcare of patients with chronic diseases through mobile applications. In this study, several models based on this methodology have been developed to calculate the basal insulin dose in patients with type I diabetes using subcutaneous insulin infusion pumps. Methods. A pilot experimental study was performed with data from 56 patients with type 1 diabetes who used insulin infusion pumps and underwent continuous glucose monitoring. Several models based on artificial intelligence techniques were developed to analyze glycemic patterns based on continuous glucose monitoring and clinical variables in order to estimate the basal insulin dose. We used neural networks (NNs), Bayesian networks (BNs), support vector machines (SVMs), and random forests (RF). We then evaluated the agreement between predicted and actual values using several statistical error measurements: mean absolute error (MAE), mean square error (MSE), root-mean-square error (RMSE), Pearson's correlation coefficient (R), and determination coefficient (R2). Results. Twenty-four different models were obtained, one for each hour of the day, with each chosen technique. Correlation coefficients obtained with RF, SVMs, NNs, and BNs were 0.9999, 0.9921, 0.0303, and 0.7754, respectively. The error increased between 06:00 and 07:00 and between 13:00 and 17:00. Conclusions. The performance of the RF technique was excellent and got very close to the actual values. Intelligence techniques could be used to predict basal insulin dose. However, it is necessary to explore the validity of the results and select the target population. Models that allow for more accurate levels of prediction should be further explored.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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