Impedance, power, and current in radiofrequency ablation: Insights from technical, ex vivo, and clinical studies.
Background: Radiofrequency (RF) power is routinely considered during RF application. In contrast, impedance has been relatively poorly studied, despite also influencing RF lesion creation. The aim of this study was to examine the influence of electric impedance on RF lesion characteristics and on cl...
| Published in: | Journal of Cardiovascular Electrophysiology Vol. 31; no. 11; pp. 2836 - 2846 |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Wiley-Blackwell
Nov2020
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=146850870&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 146850870 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10453873 GSB jtl: Journal of Cardiovascular Electrophysiology issn: 10453873 maglogo: Y pubinfo: dt: Nov2020 vid: 31 iid: 11 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 146850870 145838337 146850870 146850870 10.1111/jce.14709 146850870 ppf: 2836 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Impedance, power, and current in radiofrequency ablation: Insights from technical, ex vivo, and clinical studies. aug: au: Bourier, Felix Ramirez, F. Daniel Martin, Claire A. Vlachos, Konstantinos Frontera, Antonio Takigawa, Masateru Kitamura, Takeshi Lam, Anna Duchateau, Josselin Pambrun, Thomas Cheniti, Ghassen Derval, Nicolas Denis, Arnaud Sacher, Frédéric Hocini, Mélèze Haissaguerre, Michel Jais, Pierre affil: IHU LIRYC, Electrophysiology and Heart Modeling Institute, Fondation Bordeaux Université, Pessac‐Bordeaux, France sug: subj: Radiofrequency Ablation Electric Impedance Electric Capacitance Human Catheter Ablation Methods Electric Stimulation Ablation Techniques ab: Background: Radiofrequency (RF) power is routinely considered during RF application. In contrast, impedance has been relatively poorly studied, despite also influencing RF lesion creation. The aim of this study was to examine the influence of electric impedance on RF lesion characteristics and on clinical RF ablation parameters. Methods and Results: In the first part of the study, power and impedance were systematically varied and the resulting current was calculated using custom‐made software. In the second part of the study, ablation lesions (n = 40) were analyzed in a porcine ex vivo model. RF applications were delivered in cardiac muscle preparations with systematically varied values of electric impedance using a contact force ablation catheter. In the third part of the study, n = 3378 clinical RF applications were analyzed, power, impedance, and current data were exported and correlated with clinical patient data. 20 ± 3 W/80 Ω, 30 ± 3 W/120 Ω, 40 ± 3 W/160 Ω, and 50 ± 3 W/200 Ω RF applications resulted in 498 ± 40, 499 ± 26, 500 ± 20, and 500 ± 16 mA RF current, which were not significantly different (p =.32). Ablation lesions were significantly different in depth and diameter when applied with the same power but different impedances (p <.01); lesion sizes decreased when increasing impedance. In clinical data, a large range of delivered current (e.g., 39–40 W: 530–754 mA) was measured, due to variations in impedance. Conclusions: RF lesion creation is determined by current rather than by power. During clinical RF ablation procedures, impedance significantly influences current delivery and varies considerably between patients. Impedance and current are clinically relevant parameters that should be considered during RF ablation. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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