Superficial and Deep Foveal Avascular Zone Area Measurement in Healthy Subjects Using Two Different Spectral Domain Optical Coherence Tomography Angiography Devices.

Purpose: To compare the area of the foveal avascular zone (FAZ) in the superficial and deep retinal layers using two different spectral-domain optical coherence tomography angiography (OCTA) devices. Methods: A cross-sectional comparative study was conducted to obtain macular OCTA images from health...

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Publicado en:Journal of Ophthalmic & Vision Research Vol. 15; no. 4; pp. 517 - 524
Autores principales: Anvari, Pasha, Najafi, Amin, Mirshahi, Reza, Sardarinia, Mahsa, Ashrafkhorasani, Maryam, Kazemi, Pegah, Aghai, Gholamhoseyn, Habibi, Abbas, Falavarjani, Khalil Ghasemi
Formato: diagnostic images research tables/charts Journal Article
Publicado: Knowledge E DMCC 2020
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Knowledge E DMCC
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        10.18502/jovr.v15i4.7791
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        atl: Superficial and Deep Foveal Avascular Zone Area Measurement in Healthy Subjects Using Two Different Spectral Domain Optical Coherence Tomography Angiography Devices.
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        au:
          Anvari, Pasha
          Najafi, Amin
          Mirshahi, Reza
          Sardarinia, Mahsa
          Ashrafkhorasani, Maryam
          Kazemi, Pegah
          Aghai, Gholamhoseyn
          Habibi, Abbas
          Falavarjani, Khalil Ghasemi
        affil: Eye Research Center, The Five Senses Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
      sug:
        subj:
          Tomography, Optical Coherence
          Angiography
          Retina
          Human
          Cross Sectional Studies
          Comparative Studies
          Descriptive Statistics
          Software
      ab: Purpose: To compare the area of the foveal avascular zone (FAZ) in the superficial and deep retinal layers using two different spectral-domain optical coherence tomography angiography (OCTA) devices. Methods: A cross-sectional comparative study was conducted to obtain macular OCTA images from healthy subjects using Optovue RTVue XR Avanti (Optovue, Inc, Fremont, CA) and Spectralis HRA+OCTA (Heidelberg Engineering, Heidelberg, Germany). Two independent trained graders measured the FAZ area using automated slab segmentation. The FAZ area in the superficial and deep retinal layers were compared. Results: Twenty-three eyes of 23 subjects were included. The graders agreement was excellent (>0.86) for all measurements. The mean FAZ area was significantly larger at the superficial retinal layer as compared to the deep retinal layer on both devices (0.31 ±0.08 mm2 vs 0.26 ±0.08 mm² in Optovue and 0.55 ± 0.16 mm2 vs 0.36 ± 0.13 mm² in Spectralis, both P < 0.001). The mean FAZ area was significantly greater in the superficial and deep retinal layers using Spectralis as compared to Optovue measurements (P <0.001 for both comparisons). Conclusion: In contrast to previous reports, the FAZ area was larger in the superficial retina as compared to deep retinal layers using updated software versions. Measurements from different devices cannot be used interchangeably.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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