Joint analysis of frontal theta synchrony and white matter following mild traumatic brain injury.
Some of the most disabling aspects of mild traumatic brain injury (mTBI) include lingering deficits in executive functioning. It is known that mTBI can damage white matter tracts, but it remains unknown how this structural brain damage translates into cognitive deficits. This experiment utilized the...
| Publicado en: | Brain Imaging & Behavior Vol. 14; no. 6; pp. 2210 - 2224 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Dec2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=146869369&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 146869369 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19317557 3GSC jtl: Brain Imaging & Behavior issn: 19317557 maglogo: N pubinfo: dt: Dec2020 vid: 14 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 146869369 146869369 NLM31368085 10.1007/s11682-019-00171-y NLM31368085 146869369 ppf: 2210 ppct: 14 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Joint analysis of frontal theta synchrony and white matter following mild traumatic brain injury. aug: au: Cavanagh, James F. Rieger, Rebecca E. Wilson, J. Kevin Gill, Darbi Fullerton, Lynne Brandt, Emma Mayer, Andrew R. affil: Department of Psychology, University of New Mexico, Logan Hall, 1 University of New Mexico, MSC03 2220, 87131, Albuquerque, NM, USA sug: subj: Brain Concussion Electroencephalography Brain Physiopathology Brain Concussion Physiopathology Brain Magnetic Resonance Imaging Female Adult Male Adult: 19-44 years Female Male ab: Some of the most disabling aspects of mild traumatic brain injury (mTBI) include lingering deficits in executive functioning. It is known that mTBI can damage white matter tracts, but it remains unknown how this structural brain damage translates into cognitive deficits. This experiment utilized theta band phase synchrony to identify the dysfunctional neural operations that contribute to cognitive problems following mTBI. Sub-acute stage (< 2 weeks) mTBI patients (N = 52) and healthy matched controls (N = 32) completed a control-demanding task with concurrent EEG. Structural MRI was also collected. While there were no performance-specific behavioral differences between groups in the dot probe expectancy task, the degree of theta band phase synchrony immediately following injury predicted the degree of symptom recovery two months later. Although there were no differences in fractional anisotropy (FA) between groups, joint independent components analysis revealed that a smaller network of lower FA-valued voxels contributed to a diminished frontal theta phase synchrony network in the mTBI group. This finding suggests that frontal theta band markers of cognitive control are sensitive to sub-threshold structural aberrations following mTBI. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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