Continuous Preparative SEC for Purification of "Difficult-to-Manufacture" Proteins-A Feasibility Study.
The advent of new antibody formats, such as multispecific antibodies or Fc-fusion proteins, imposes new challenges on downstream processing. Classical Protein A or ion exchange chromatography may not be capable of delivering adequate product quality if impurities display similar physicochemical prop...
| Publicado en: | BioPharm International Vol. 33; no. 11; pp. 28 - 35 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
MJH Life Sciences
Nov2020
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| Acceso en línea: | Ver este registro en EBSCOhost |