Separability of Acute Cerebral Infarction Lesions in CT Based Radiomics: Toward Artificial Intelligence-Assisted Diagnosis.

This study aims at analyzing the separability of acute cerebral infarction lesions which were invisible in CT. 38 patients, who were diagnosed with acute cerebral infarction and performed both CT and MRI, and 18 patients, who had no positive finding in either CT or MRI, were enrolled. Comparative st...

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Publicado en:BioMed Research International pp. 1 - 9
Autores principales: Guan, Yun, Wang, Peng, Wang, Qi, Li, Peihao, Zeng, Jianchao, Qin, Pinle, Meng, Yanfeng
Formato: diagnostic images equations & formulas pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 11/16/2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 11/16/2020
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2020/8864756
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        atl: Separability of Acute Cerebral Infarction Lesions in CT Based Radiomics: Toward Artificial Intelligence-Assisted Diagnosis.
      aug:
        au:
          Guan, Yun
          Wang, Peng
          Wang, Qi
          Li, Peihao
          Zeng, Jianchao
          Qin, Pinle
          Meng, Yanfeng
        affil: North University of China-Taiyuan Central Hospital Joint Innovation Institute, 3 Xueyuan Road, Taiyuan, Shanxi 030051, China
      sug:
        subj:
          Cerebral Infarction Diagnosis
          Brain Pathology
          Tomography, X-Ray Computed
          Image Interpretation, Computer Assisted
          Human
          Magnetic Resonance Imaging
          Artificial Intelligence
      ab: This study aims at analyzing the separability of acute cerebral infarction lesions which were invisible in CT. 38 patients, who were diagnosed with acute cerebral infarction and performed both CT and MRI, and 18 patients, who had no positive finding in either CT or MRI, were enrolled. Comparative studies were performed on lesion and symmetrical regions, normal brain and symmetrical regions, lesion, and normal brain regions. MRI was reconstructed and affine transformed to obtain accurate lesion position of CT. Radiomic features and information gain were introduced to capture efficient features. Finally, 10 classifiers were established with selected features to evaluate the effectiveness of analysis. 1301 radiomic features were extracted from candidate regions after registration. For lesion and their symmetrical regions, there were 280 features with information gain greater than 0.1 and 2 features with information gain greater than 0.3. The average classification accuracy was 0.6467, and the best classification accuracy was 0.7748. For normal brain and their symmetrical regions, there were 176 features with information gain greater than 0.1, 1 feature with information gain greater than 0.2. The average classification accuracy was 0.5414, and the best classification accuracy was 0.6782. For normal brain and lesions, there were 501 features with information gain greater than 0.1 and 1 feature with information gain greater than 0.5. The average classification accuracy was 0.7480, and the best classification accuracy was 0.8694. In conclusion, the study captured significant features correlated with acute cerebral infarction and confirmed the separability of acute lesions in CT, which established foundation for further artificial intelligence-assisted CT diagnosis.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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