Minimal or reasonable? Considering the ethical threshold for research risks to nonconsenting bystanders and implications for nonconsenting participants.

When research poses risks to non‐participant bystanders, it is not always practicable to obtain their consent. One approach to assessing how much research risk may be imposed on nonconsenting bystanders is to examine analogous circumstances, including risk thresholds deemed acceptable for nonconsent...

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Publicado en:Bioethics Vol. 34; no. 9; pp. 923 - 933
Autor principal: Fernandez Lynch, Holly
Formato: Artículo
Publicado: Wiley-Blackwell Nov2020
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Minimal or reasonable? Considering the ethical threshold for research risks to nonconsenting bystanders and implications for nonconsenting participants.
      aug:
        au: Fernandez Lynch, Holly
        affil: Department of Medical Ethics and Health Policy, Perelman School of Medicine, University of Pennsylvania
      su:
        United States
        Bioethics
        Informed consent (Medical law)
        Research ethics
        Human research subjects
        Risk assessment
        Risk management in business
        Patient selection
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        subj:
          Bioethics
          Informed consent (Medical law)
          Research ethics
          Human research subjects
          United States
          Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
          Risk assessment
          Risk management in business
          Patient selection
      keyword:
        bystanders
        challenge trial
        minimal risk
        reasonable risk
        research risk
        risk thresholds
        third parties
        bystanders
        challenge trial
        minimal risk
        reasonable risk
        research risk
        risk thresholds
        third parties
      ab: When research poses risks to non‐participant bystanders, it is not always practicable to obtain their consent. One approach to assessing how much research risk may be imposed on nonconsenting bystanders is to examine analogous circumstances, including risk thresholds deemed acceptable for nonconsenting research participants and for nonconsensual risks imposed outside the research setting. For nonconsenting participants, US research regulations typically limit risks to those deemed to be "minimal." Outside the research context, US tort law tolerates a more flexible "reasonable" risk threshold. This article advances a preliminary case that nonconsenting participants and nonconsenting bystanders exposed to similar research risks may be entitled to the same level of protection, but that risks generated by research may not be special in kind. Thus, limiting research risks to those that are "reasonable," rather than demanding that they be held to the "minimal" standard, may be the best approach for both nonconsenting participants and nonconsenting bystanders. Further work is needed to establish whether the descriptive standards used to support the analogies relied on here are normatively justifiable, as well as the extent to which the minimal risk standard and the reasonable risk standard would lead to meaningfully different outcomes in practice.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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