Bystanders and ethical review of research: Proceed with caution.

Scientists seeking to conduct research with human subjects must first submit their proposals to research ethics committees (Institutional Review Boards [IRBs], in the United States). Some of these studies pose risks to "bystanders," i.e., people who may be affected by the research but who are not en...

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Publicado en:Bioethics Vol. 34; no. 9; pp. 937 - 941
Autor principal: Wikler, Daniel
Formato: Artículo
Publicado: Wiley-Blackwell Nov2020
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Bystanders and ethical review of research: Proceed with caution.
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        au: Wikler, Daniel
        affil: Department of Global Health and Population, Harvard School of Public Health, Boston Massachusetts,
      su:
        United States
        Government agencies
        Medical research
        Government regulation
        Human research subjects
        Institutional review boards
        Cost analysis
        Professional practice
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          Government agencies
          Medical research
          Government regulation
          Human research subjects
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          Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
          Institutional review boards
          Cost analysis
          Professional practice
      keyword:
        bystanders
        ethical review
        IRBs
        research ethics
        research risk
        risk
        bystanders
        ethical review
        IRBs
        research ethics
        research risk
        risk
      ab: Scientists seeking to conduct research with human subjects must first submit their proposals to research ethics committees (Institutional Review Boards [IRBs], in the United States). Some of these studies pose risks to "bystanders," i.e., people who may be affected by the research but who are not enrolled as study subjects. Should IRBs expand their scope to include oversight over possible harms to bystanders as well as research subjects? This paper presents arguments against this step. Prior review of research with human subjects, despite its evident burden on the research enterprise, is a necessary caution, because the tension between the objectives of humane treatment of research subjects and sound scientific design and procedure has in the past led to serious abuses. This rationale is inapplicable in the case of bystanders. Moreover, in view of the many and varied effects of both research practices and scientific advances on the broader public over time, those who may be considered to be "bystanders" may potentially expand without limit; requiring IRBs to anticipate these distant and long‐term effects as part of prior ethical review could greatly increase its burden and its deterrent effect on research. While conducting research without concern for serious potential harm to bystanders may be irresponsible and unethical, expanding the scope of prior review by IRBs to include risks to bystanders is not required by the principles governing human subjects research, and the costs and burdens of this expansion may outweigh any expected gains.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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