Genetic testing costs and compliance with clinical best practices.

We sought to determine the costs of genetic testing and compliance with published guidelines and clinical best practices at our institution. A cost analysis was performed comparing the costs of ordered tests to the cost of the recommended testing. This was an approved quality improvement project at...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of Genetic Counseling Vol. 29; no. 6; pp. 1186 - 1192
Autores principales: Montanez, Kathleen, Berninger, Taylor, Willis, Mary, Harding, Aaron, Lutgendorf, Monica A.
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Dec2020
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=147379004&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 147379004
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        10597700
        41A
      jtl: Journal of Genetic Counseling
      issn: 10597700
      maglogo: N
    pubinfo:
      dt: Dec2020
      vid: 29
      iid: 6
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
    artinfo:
      ui:
        147379004
        147379004
        147379004
        10.1002/jgc4.1285
        147379004
      ppf: 1186
      ppct: 6
      formats:
        fmt:
          – @attributes:
              type: T
          – @attributes:
              type: P
      tig:
        atl: Genetic testing costs and compliance with clinical best practices.
      aug:
        au:
          Montanez, Kathleen
          Berninger, Taylor
          Willis, Mary
          Harding, Aaron
          Lutgendorf, Monica A.
        affil: Department of Obstetrics and Gynecology, Naval Medical Center San Diego, San Diego California
      sug:
        subj:
          Genetic Screening Economics
          Costs and Cost Analysis
          Quality Improvement
          Diagnostic Tests, Routine
          Human
          Academic Medical Centers California
          California
          Activated Protein C Resistance
          alpha-Thalassemia
          Hemochromatosis
          Record Review
          Practice Guidelines
          Cost Savings
          Cost Benefit Analysis
          Genetic Counseling
      ab: We sought to determine the costs of genetic testing and compliance with published guidelines and clinical best practices at our institution. A cost analysis was performed comparing the costs of ordered tests to the cost of the recommended testing. This was an approved quality improvement project at a tertiary teaching hospital in California. We identified charts associated with the genetic testing billing codes for common genetic tests through our contracted laboratory (cystic fibrosis genotyping, Breast cancer susceptibility gene (BRCA 1&2), Methylenetetrahydrofolate reductase (MTHFR), factor V Leiden (FVL), prothrombin gene pathogenic variant, alpha‐thalassemia, hemochromatosis, and cell‐free fetal DNA). Charts were reviewed retrospectively by a licensed, certified genetic counselor to assess the compliance with published clinical practice guidelines identified on GeneReviews and the American College of Obstetricians and Gynecologists (ACOG). Tests were classified as: appropriate, misordered/not indicated, misordered/false reassurance, and misordered/inadequate. We performed a cost analysis for the recommended test changes. We reviewed 114 charts over a three‐month period. Forty‐four (38.6%) of the tests were misordered based on published clinical practice guidelines: 24 (21%) were misordered/not indicated, 8 (7%) were misordered/false reassurance, and 12 (10.5%) were misordered/inadequate. Costs of ordered testing ($75,177) were compared to recommended testing after review ($54,265), with a total cost savings of $20,912. In clinical practice, over one‐third of genetic tests reviewed were misordered. As these tests are a small fraction of all genetic tests at our institution, future studies should broaden the scope of testing evaluated to understand the magnitude of this problem and potential cost savings. Genetic counselor review and involvement in genetic test ordering can decrease inappropriate healthcare expenditures and improve patient care.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N