CYTOMEGALOVIRUS RETINITIS AND CRYPTOCOCCUS MENINGITIS WITH PAPILITIS IN PAEDIATRIC AIDS PATIENT.

Background: The incidence of ocular complications in HIV-infected patients varies from 42% to 75% and some of these complications may lead to blindness. Here we report a rare case of retroviral disease with cytomegalovirus (CMV) retinitis in one eye and papillitis secondary to cryptococcus meningiti...

Full description

Bibliographic Details
Published in:International Journal of Public Health & Clinical Sciences (IJPHCS) Vol. 7; no. 5; pp. 112 - 121
Main Authors: Chan Hui Tze, Mansurali, Vanessa N., Wan Hitam, Wan-Hazabbah, Tajudin, Liza Sharmini Ahmad
Format: case study pictorial Journal Article
Published: Community Health Society Malaysia 2020
Online Access:View this record in EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=147572451&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 147572451
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        22897577
        LF9G
      jtl: International Journal of Public Health & Clinical Sciences (IJPHCS)
      issn: 22897577
      maglogo: N
    pubinfo:
      dt: 2020
      vid: 7
      iid: 5
      pid: 46694
      pub: Community Health Society Malaysia
    artinfo:
      ui:
        147572451
        147572451
        147572451
        147572451
      ppf: 112
      ppct: 9
      formats:
      tig:
        atl: CYTOMEGALOVIRUS RETINITIS AND CRYPTOCOCCUS MENINGITIS WITH PAPILITIS IN PAEDIATRIC AIDS PATIENT.
      aug:
        au:
          Chan Hui Tze
          Mansurali, Vanessa N.
          Wan Hitam, Wan-Hazabbah
          Tajudin, Liza Sharmini Ahmad
        affil: Department of Ophthalmology, School of Medical Sciences, Health Campus Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
      sug:
        subj:
          Cytomegalovirus Retinitis Diagnosis
          Meningitis, Cryptococcal Diagnosis
          Optic Neuritis Diagnosis
          Acquired Immunodeficiency Syndrome In Adolescence
          HIV Infections In Adolescence
          Optic Neuritis Risk Factors
          Adolescence
          Female
          Cytomegalovirus Retinitis Drug Therapy
          Meningitis, Cryptococcal Drug Therapy
          Optic Neuritis Drug Therapy
          Ganciclovir Therapeutic Use
          Amphotericin B Therapeutic Use
          Heterocyclic Compounds Therapeutic Use
          Fluconazole Therapeutic Use
          Antiretroviral Therapy, Highly Active
          Ophthalmoscopy
          Adolescent: 13-18 years
          Female
      ab: Background: The incidence of ocular complications in HIV-infected patients varies from 42% to 75% and some of these complications may lead to blindness. Here we report a rare case of retroviral disease with cytomegalovirus (CMV) retinitis in one eye and papillitis secondary to cryptococcus meningitis in the other eye. Case Report: A 14 year old Malay girl who was diagnosed with AIDS since birth through vertical transmission presented with fever, headache, seizure and chronic poor vision in the right eye for about 8 months duration. She was on antiretroviral therapy (HAART). Visual acuity in the right eye was only perception to light and in the left eye was 6/9. Both anterior segments were unremarkable. Fundoscopy of the right eye showed generalised shallow retinal detachment and left swollen hyperaemic disc. Computed tomography (CT) scan of the brain was normal. Lumbar puncture opening pressure was normal as well. A diagnosis of retroviral disease with cryptococcal meningitis, right advanced CMV retinitis and left papillitis was made. Patient was treated with HAART regime, ganciclovir, amphotericin B, flucytosine and fluconazole. The papillitis responded well to treatment. However, the CMV retinitis persisted. Conclusion: In conclusion, AIDS patients are susceptible to multiple opportunistic infection that may co-exist with different severity in either eye. Prompt diagnosis and early medical intervention may preserve vision and improve life expectancy.
      pubtype: Academic Journal
      doctype:
        case study
        pictorial
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N