Positive and negative aspects of social relations and low-grade inflammation in Copenhagen Aging and Midlife Biobank.
The association between social relations and health outcomes is well described, but pathways are relatively poorly understood. Inflammation has been suggested as a potential physiological pathway, linking social relations to adverse health outcomes. However, previous studies have shown ambiguous res...
| Publicado en: | European Journal of Ageing Vol. 17; no. 4; pp. 531 - 547 |
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| Autores principales: | , , , , , |
| Formato: | Artículo |
| Publicado: |
Springer Nature
Dec2020
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=147718676&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 147718676 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 16139372 3RAL jtl: European Journal of Ageing issn: 16139372 maglogo: N pubinfo: dt: Dec2020 vid: 17 iid: 4 pid: 237 pub: Springer Nature artinfo: ui: 147718676 10.1007/s10433-020-00561-y ppf: 531 ppct: 16 formats: fmt: – @attributes: type: T – @attributes: type: P size: 625KB tig: atl: Positive and negative aspects of social relations and low-grade inflammation in Copenhagen Aging and Midlife Biobank. aug: au: Nilsson, Charlotte Juul Nørgaard, Signe Foverskov, Else Bruunsgaard, Helle Andersen, Per Kragh Lund, Rikke affil: Section of Social Medicine, Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen K, Denmark Center for Healthy Aging, University of Copenhagen, Blegsdamsvej 3B, 2200, Copenhagen K, Denmark Department of Clinical Immunology 7631 and Centre of Inflammation and Metabolism and Centre for Physical Activity Research, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark Section of Biostatistics, Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen K, Denmark su: Denmark Sex distribution Aging Interpersonal relations Social classes Multiple regression analysis Questionnaires Descriptive statistics Odds ratio Inflammation Confidence intervals sug: subj: Sex distribution Aging Interpersonal relations Social classes Denmark Multiple regression analysis Questionnaires Descriptive statistics Odds ratio Inflammation Confidence intervals keyword: Gender Low-grade inflammation Social relations Social strain Socioeconomic position Gender Low-grade inflammation Social relations Social strain Socioeconomic position ab: The association between social relations and health outcomes is well described, but pathways are relatively poorly understood. Inflammation has been suggested as a potential physiological pathway, linking social relations to adverse health outcomes. However, previous studies have shown ambiguous results and have for the vast majority been based on studies small in sample size. The aim of the present study is to examine the association between comprehensive measures of structural and positive as well as negative functional aspects of social relations, across four relational domains—partner/spouse, children, other family and friends, and the level of systemic low-grade inflammation in a large population-based middle-aged cohort and to examine variation by gender and socioeconomic position in these associations. The study comprised of 5576 participants in the Copenhagen Aging and Midlife Biobank. The inflammatory biomarkers collected in late midlife included C-reactive protein, Interleukin-6, and TNF-alpha. Multiple linear regression models were implemented to explore associations between social relations and inflammatory measures controlling for gender, age, socioeconomic position, marital status, early major lifeevents and morbidity. Results show weak and ambiguous associations in all analyses. There were no strong indications of interaction with socioeconomic position. Concluding cautiously, men appear to be more vulnerable toward living alone and low contact frequency with family compared to women as regards high level of low-grade inflammation. In conclusion, this large-scale population-based study among middle-aged men and women showed no association between social relations and low-grade inflammation. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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