SQUAMOUS CELL CARCINOMA IN EPIDERMOLYSIS BULLOSA.
Epidermolysis bullosa (EB) refers to a group of rare genetically inherited skin fragility disorders where the skin and mucous membrane blister or shear in response to minimal friction or trauma. The four main types range in severity and its impact on an individual's quality of life. The shared commo...
| Publicado en: | Dermatological Nursing Vol. 19; no. 4; pp. 10 - 17 |
|---|---|
| Autores principales: | , |
| Formato: | case study pictorial review tables/charts Journal Article |
| Publicado: |
British Dermatological Nursing Group
Dec2020
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=147752733&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 147752733 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14773368 BM2D jtl: Dermatological Nursing issn: 14773368 maglogo: N pubinfo: dt: Dec2020 vid: 19 iid: 4 pid: 70069 pub: British Dermatological Nursing Group place: , <Blank> artinfo: ui: 147752733 147752733 147752733 147752733 ppf: 10 ppct: 7 formats: fmt: @attributes: type: P tig: atl: SQUAMOUS CELL CARCINOMA IN EPIDERMOLYSIS BULLOSA. aug: au: Downe, Annette Clapham, Jane affil: EB CNS at St John's Institute of Dermatology Guy's and St Thomas NHS Foundation Trust sug: subj: Carcinoma, Squamous Cell Diagnosis Epidermolysis Bullosa Classification Skin Diseases, Genetic Practice Guidelines Dermatology Nursing Epidermolysis Bullosa Familial and Genetic Carcinoma, Squamous Cell Therapy Carcinoma, Squamous Cell Risk Factors Collagen Early Diagnosis Male Aged Lymph Nodes Neoplasm Metastasis Epidermal Growth Factors Chemotherapy, Cancer Methods Female Adult Amputation Rare Diseases Aged: 65+ years Adult: 19-44 years Male Female ab: Epidermolysis bullosa (EB) refers to a group of rare genetically inherited skin fragility disorders where the skin and mucous membrane blister or shear in response to minimal friction or trauma. The four main types range in severity and its impact on an individual's quality of life. The shared commonality in all types of EB are life-long wounding with cutaneous and systemic complications. However, people with more severe forms of EB are at increased risk of developing aggressive squamous cell carcinoma (SCC) often leading to an early death. Unlike in the general population, these tumours tend to develop rapidly and metastasise. This article will focus on the difficulty of diagnosis due to the broad clinical appearance of tumours and underlines the importance of a multidisciplinary patient centred approach which focuses on early detection and treatment of these aggressive SCCs. Advances in targeted therapies has the potential of changing treatment, but the current gold standard treatment remains surgical excision. The case studies demonstrate the vital role that the expert patient plays in their care which is key to optimising the best outcome. pubtype: Academic Journal doctype: case study pictorial review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|