The "Fortilat" Randomized Clinical Trial Follow-Up: Auxological Outcome at 18 Months of Age.
Human milk fortification is a routine clinical practice for feeding preterm infants. We hypothesized that donkey milk can be a suitable basis for developing an innovative human milk fortifier. Our randomized controlled single-blind clinical trial, named "Fortilat", evaluated the feeding tolerance, g...
| Publicado en: | Nutrients Vol. 12; no. 12; pp. 3730 - 3731 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
MDPI
Dec2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=147824229&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 147824229 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20726643 B0TT jtl: Nutrients issn: 20726643 maglogo: N pubinfo: dt: Dec2020 vid: 12 iid: 12 pid: 97109 pub: MDPI artinfo: ui: 147824229 147824229 147824229 10.3390/nu12123730 147824229 ppf: 3730 ppct: 1 formats: tig: atl: The "Fortilat" Randomized Clinical Trial Follow-Up: Auxological Outcome at 18 Months of Age. aug: au: Peila, Chiara Spada, Elena Bertino, Enrico Deantoni, Sonia Percivati, Federica Moro, Guido E. Giribaldi, Marzia Cavallarin, Laura Cresi, Francesco Coscia, Alessandra affil: Department of Public Health and Pediatric, Neonatal Unit of Turin University, Via Ventimiglia 3, 10126 Turin, Italy sug: subj: Food, Fortified Milk, Human Horses Milk Infant Feeding Evaluation Growth Evaluation Treatment Outcomes Proteins Human Randomized Controlled Trials Infant, Premature Infant Development Hospitals Office Visits Body Weight Head Circumference Pretest-Posttest Design Comparative Studies ab: Human milk fortification is a routine clinical practice for feeding preterm infants. We hypothesized that donkey milk can be a suitable basis for developing an innovative human milk fortifier. Our randomized controlled single-blind clinical trial, named "Fortilat", evaluated the feeding tolerance, growth and clinical short-term outcomes in a population of preterm infants fed with a novel multi-component fortifier and a protein concentrate derived from donkey milk. The aim of the current study is to extend the previous findings and to evaluate the auxological outcomes of the infants enrolled in the "Fortilat" trial at 18 months of age. In the previous trial "Fortilat", the fortification protocol followed was the same for the two groups, and the two diets were designed to be isoproteic and isocaloric. All infants enrolled in the trial were included in a premature infant developmental evaluation program consisting of hospital visits at 40 ± 1 weeks of postmenstrual age, and at 6, 12 and 18 months of corrected age. Weight, head circumference and length were expressed in z-score using neonatal Intergrowth21st and INeS charts at birth, and WHO 0–5 years growth charts at 18 months. 122 children (Bovine-arm = 62, Donkey-arm = 60) were included in this study. All the observations were recorded in the interval of 18 ± 3 months of the correct age. The two groups did not differ for head circumference, length or weight at 18 months of age. Our data show that fortifiers derived from donkey milk had not different long term auxological outcomes of standard bovine-derived fortifier, but the new donkey milk fortifier was well tolerated in our population. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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