Maximum Voluntary Ventilation and Its RelationshipWith Clinical Outcomes in Subjects With COPD.
BACKGROUND: Previous studies have reported that maximum voluntary ventilation (MVV) may be better associated with commonly used outcomes in COPD than FEV1 and may provide information on respiratory mechanics. In this study, we aimed to investigate the relationship between MVV and clinical outcomes i...
| Publicado en: | Respiratory Care Vol. 66; no. 1; pp. 79 - 87 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Jan2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=147933476&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 147933476 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: Jan2021 vid: 66 iid: 1 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 147933476 147933476 147933476 10.4187/respcare.07855 147933476 ppf: 79 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Maximum Voluntary Ventilation and Its RelationshipWith Clinical Outcomes in Subjects With COPD. aug: au: Andrello, Ana Carolina Donaria, Leila de Castro, Larissa A. Belo, Letícia F. Schneider, Lorena P. Machado, Felipe V. C. Ribeiro, Marcos Probst, Vanessa S. Hernandes, Nidia A. Pitta, Fabio affil: Laboratory of Research in Respiratory Physiotherapy, Physiotherapy Department, State University of Londrina, Londrina, Brazil sug: subj: Pulmonary Disease, Chronic Obstructive Lung Volume Measurements Treatment Outcomes Forced Expiratory Volume Human Male Female Middle Age Aged Cross Sectional Studies Lung Physiology Retrospective Design Spirometry Respiratory Muscles Physiology Manometry Respiratory Function Tests Activities of Daily Living Descriptive Statistics Spearman's Rank Correlation Coefficient Data Analysis Software Clinical Assessment Tools Scales Questionnaires Middle Aged: 45-64 years Aged: 65+ years Male Female ab: BACKGROUND: Previous studies have reported that maximum voluntary ventilation (MVV) may be better associated with commonly used outcomes in COPD than FEV1 and may provide information on respiratory mechanics. In this study, we aimed to investigate the relationship between MVV and clinical outcomes in COPD and to verify whether MVV predicts these outcomes better than FEV1. METHODS: We conducted a cross-sectional study involving individuals with COPD. Lung function was assessed with spirometry; maximum inspiratory and expiratory pressures (PImax and PEmax, respectively) were assessed with manuvacuometry; and functional exercise capacity was assessed with the 6-min-walk test (6MWT). Dyspnea was assessed with the modified Medical Research Council (mMRC) scale; functional status was assessed with the modified Pulmonary Functional Status and Dyspnea Questionnaire (PFSDQ-m); and health status was assessed with the COPD Assessment Test (CAT). Correlations were verified with the Spearman coefficient, and stepwise multiple linear regression models investigated the predictors of clinical outcomes. RESULTS: Our study included 157 subjects: 82 males; median (interquartile range) age 66 (61-73) y; FEV1 46 (33-57) % predicted; 6MWT 86 (76-96) % predicted; PFSDQ-m total score 34 (14-57); and CAT total score 13 (7-19). Moderate correlations were found between MVV and PImax (r = 0.40), 6MWT (r = 0.50), mMRC (r = -0.56), and total scores on the PFSDQ-m (r = -0.40) and the CAT (r = -0.54). In the regression models, MVV was a predictor of almost all clinical outcomes, unlike FEV1. CONCLUSIONS: MVV correlates moderately with clinical outcomes commonly used in the evaluation of individuals with COPD, and MVV is a better predictor of respiratory muscle strength, functional exercise capacity, and patient-reported outcomes than FEV1. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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