A Treatment to Eliminate SARS-CoV-2 Replication in Human Airway Epithelial Cells Is Safe for Inhalation as an Aerosol in Healthy Human Subjects.

BACKGROUND: Low airway surface pH is associated with many airway diseases, impairs antimicrobial host defense, and worsens airway inflammation. Inhaled Optate is designed to safely raise airway surface pH and is well tolerated in humans. Raising intracellular pH partially prevents activation of SARS...

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Publicado en:	Respiratory Care Vol. 66; no. 1; pp. 113 - 120
Autores principales:	Davis, Michael D., Clemente, Tatiana M., Giddings, Olivia K., Ross, Kristie, Cunningham, Rebekah S., Smith, Laura, Simpson, Edward, Yunlong Liu, Kloepfer, Kirsten, Ramsey, I. Scott, Yi Zhao, Robinson, Christopher M., Gilk, Stacey D., Gaston, Benjamin
Formato:	pictorial research tables/charts Journal Article
Publicado:	Mary Ann Liebert, Inc. Jan2021
Acceso en línea:	Ver este registro en EBSCOhost