بررسی خصوصیات فیزیکوشیمیایی و متغیرهای فارماکوگنوزی مان انذروت براساس دستورالعمل سازمان بهداشت جهانی.

Background: Anzaroot is a manna produced from Astragalus sarcocola Dymock (Family Leguminosae) that is widely distributed in Fars, Kerman, Baluchestan and Hormozgan in Iran. Since the study of the physicochemical properties and quality control (QC) of herbal materials results in the validation and s...

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Published in:Medical Journal of Tabriz University of Medical Sciences & Health Services Vol. 42; no. 5; pp. 71 - 79
Main Authors: هادی اسماعیلی, علی داوودی, مسعود آزادبخت, محمد آزادبخت
Format: pictorial research tables/charts Journal Article
Published: Tabriz University of Medical Sciences Dec2020/Jan2021
Online Access:View this record in EBSCOhost
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      dt: Dec2020/Jan2021
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      pub: Tabriz University of Medical Sciences
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        atl: بررسی خصوصیات فیزیکوشیمیایی و متغیرهای فارماکوگنوزی مان انذروت براساس دستورالعمل سازمان بهداشت جهانی.
      aug:
        au:
          هادی اسماعیلی
          علی داوودی
          مسعود آزادبخت
          محمد آزادبخت
        affil: واحد تحقیق و توسعه، شرکت داروسازی نیاک، گرگان، ایران.
      sug:
        subj:
          Medicine, Traditional Iran
          Plants, Medicinal Analysis
          Phytochemicals Analysis
          World Health Organization
          Human
          Iran
          Microscopy
          Descriptive Statistics
          Solubility
          Ethanol
          Flavonoids
          Quercetin
      ab: Background: Anzaroot is a manna produced from Astragalus sarcocola Dymock (Family Leguminosae) that is widely distributed in Fars, Kerman, Baluchestan and Hormozgan in Iran. Since the study of the physicochemical properties and quality control (QC) of herbal materials results in the validation and standardization for clinical uses, in accordance with World Health Organization (WHO) guidelines, it is necessary to carry out for Anzaroot which has indication in traditional medicine. Methods: Anzaroot was identified and determinated scientific name by a systematic specialist after purchasing from Niak pharmaceutical co. in gorgan. Physicochemical and pharmacognostical properties of Anzaroot have been determinated According to the WHO guidlines. Results: Anzaroot is a very bitter, crisp and fragile manna and non-stick in dry state, which is seen as separate binary grains under the microscope. The moisture content, foreign matter, sucrose content, total ash and watersoluble ash were reported 5.25 ± 0.2, 2.8 ± 0.2, 12.09 ± 0.04, 9.8 ± 0.5 and 2.9±0.15, respectively. It has significant foaming index, 72% Solublity in water and less than 50% in 96% ethanol and not swelling index. The levels of lead, mercury and cadmium were 0.0006, 0.0002 and 0.0007 ppm and total flavonoid content was reported 18.61 μg/ml with respect to standard Quercetin at 415 nm. Conclusion: This study can be a novel idea for the discovery or development of pharmaceutical products based on Anzaroot of Iran and its diverse therapeutic properties, such as the common cold, contusion, and bone fracture in traditional medicine.
      pubtype: Academic Journal
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        research
        tables/charts
        Journal Article
      ougenre: Article
    language: Persian
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