Multicenter Study of Quantitative SPECT: Reproducibility of 99mTc Quantitation Using a Conjugated-Gradient Minimization Reconstruction Algorithm.
This multicenter study aimed to determine the reproducibility of quantitative SPECT images reconstructed using a commercially available method of ordered-subset conjugate-gradient minimization. Methods: A common cylindric phantom containing a 100 kBq/mL concentration of 99mTc-pertechnetate solution...
| Publicado en: | Journal of Nuclear Medicine Technology Vol. 49; no. 1; pp. 1 - 34 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Society of Nuclear Medicine
Jan2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=147990793&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 147990793 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00914916 H7Q jtl: Journal of Nuclear Medicine Technology issn: 00914916 maglogo: N pubinfo: dt: Jan2021 vid: 49 iid: 1 pid: 2576 pub: Society of Nuclear Medicine place: Reston, Virginia artinfo: ui: 147990793 147990793 NLM33419954 147990793 10.2967/jnmt.120.256131 NLM33419954 147990793 ppf: 1 ppct: 33 formats: fmt: @attributes: type: P tig: atl: Multicenter Study of Quantitative SPECT: Reproducibility of 99mTc Quantitation Using a Conjugated-Gradient Minimization Reconstruction Algorithm. aug: au: Kyohei Okuda Daisuke Hasegawa Takashi Kamiya Hajime Ichikawa Takuro Umeda Takushi Ohkubo Kenta Miwa Okuda, Kyohei Hasegawa, Daisuke Kamiya, Takashi Ichikawa, Hajime Umeda, Takuro Ohkubo, Takushi Miwa, Kenta affil: Department of Clinical Radiology, Tottori University Hospital; 36-1 Nishi-cho, Yonago, Tottori 683-8504, Japan sug: subj: Algorithms Tomography, Emission-Computed, Single-Photon Reproducibility of Results Technetium Phantoms, Imaging Comparative Studies Multicenter Studies Evaluation Research Validation Studies Scales ab: This multicenter study aimed to determine the reproducibility of quantitative SPECT images reconstructed using a commercially available method of ordered-subset conjugate-gradient minimization. Methods: A common cylindric phantom containing a 100 kBq/mL concentration of 99mTc-pertechnetate solution in a volume of 7 L was scanned under standard imaging conditions at 6 institutions using the local clinical protocol of each. Interinstitutional variation among the quantitative SPECT images was evaluated using the coefficient of variation. Dose calibrator accuracy was also investigated by measuring the same lot of commercially available 99mTc vials at each institution. Results: The respective radioactivity concentrations under standard and clinical conditions ranged from 95.71 ± 0.60 (mean ± SD) to 108.35 ± 0.36 kBq/mL and from 96.78 ± 0.64 to 108.49 ± 0.11 kBq/mL, respectively. Interinstitutional variation in radioactivity concentration was 4.20%. The bias in the radioactivity concentrations in SPECT images was associated with the accuracy of the dose calibrator at each institution. Conclusion: The reproducibility of the commercially available quantitative SPECT reconstruction method is high and comparable to that of PET, for comparatively large (∼7 L), homogeneous objects. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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