Smoothed particle hydrodynamics simulation of biphasic soft tissue and its medical applications.
Modeling the coupled fluid and elastic mechanics of blood perfused soft tissues is important for medical applications. In particular, the current study aims to capture the effect of tissue swelling and the transport of blood through damaged tissue under bleeding or hemorrhaging conditions. The soft...
| Publicado en: | Medical & Biological Engineering & Computing Vol. 59; no. 1; pp. 227 - 243 |
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| Autores principales: | , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Jan2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=148139431&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 148139431 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Jan2021 vid: 59 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 148139431 148007266 148139431 NLM33415698 10.1007/s11517-020-02283-w NLM33415698 148139431 ppf: 227 ppct: 16 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Smoothed particle hydrodynamics simulation of biphasic soft tissue and its medical applications. aug: au: Chang, Yi-Jui Benharash, Peyman Dutson, Erik P. Eldredge, Jeff D. affil: Mechanical and Aerospace Engineering Department, University of California, Los Angeles, CA, USA sug: subj: Physiochemical Phenomena Computer Simulation Arthritis Impact Measurement Scales ab: Modeling the coupled fluid and elastic mechanics of blood perfused soft tissues is important for medical applications. In particular, the current study aims to capture the effect of tissue swelling and the transport of blood through damaged tissue under bleeding or hemorrhaging conditions. The soft tissue is considered a dynamic poro-hyperelastic material with blood-filled voids. A biphasic formulation-effectively, a generalization of Darcy's law-is utilized, treating the phases as occupying fractions of the same volume. A Stokes-like friction force and a pressure that penalizes deviations from volume fractions summing to unity serve as the interaction force between solid and liquid phases. The resulting equations for both phases are discretized with the method of smoothed particle hydrodynamics (SPH). The solver is validated separately on each phase and demonstrates good agreement with exact solutions in test problems. Simulations of oozing, hysteresis, swelling, drying and shrinkage, and tissue fracturing and hemorrhage are shown in the paper. Graphical Abstract In the paper, a new methodology for the numerical simulation of the full dynamic response of blood-perfused soft tissues was developed. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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