Analysis of an individual‐based influenza epidemic model using random forest metamodels and adaptive sequential sampling.

This study proposes a three‐step procedure for the analysis of input–response relationships of dynamic models, which enables the analyst to develop a better understanding about the dynamics of the system. The main building block of the procedure is a random forest metamodel capturing the input–outpu...

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Publicado en:Systems Research & Behavioral Science Vol. 37; no. 6; pp. 936 - 959
Autores principales: Edali, Mert, Yücel, Gönenç
Formato: Artículo
Publicado: Wiley-Blackwell Nov2020
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2020
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      pub: Wiley-Blackwell
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        148147860
        10.1002/sres.2763
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        atl: Analysis of an individual‐based influenza epidemic model using random forest metamodels and adaptive sequential sampling.
      aug:
        au:
          Edali, Mert
          Yücel, Gönenç
        affil:
          Department of Industrial Engineering, Bogazici University, Istanbul, Turkey
          Department of Industrial Engineering, Yildiz Technical University, Istanbul, Turkey
          Chicago Center for HIV Elimination, University of Chicago, Chicago IL,, USA
          Department of Medicine, University of Chicago, Chicago IL,, USA
      su:
        Epidemics
        Immunization
        Influenza epidemiology
        Statistical models
        Random forest algorithms
      sug:
        subj:
          Epidemics
          Immunization
          Influenza epidemiology
          Statistical models
          Random forest algorithms
      keyword:
        adaptive sequential sampling
        FluTE
        individual‐based modelling
        metamodeling
        rule extraction
        adaptive sequential sampling
        FluTE
        individual‐based modelling
        metamodeling
        rule extraction
      ab: This study proposes a three‐step procedure for the analysis of input–response relationships of dynamic models, which enables the analyst to develop a better understanding about the dynamics of the system. The main building block of the procedure is a random forest metamodel capturing the input–output relationships. We utilize an active learning approach as the second step to improve the accuracy of the metamodel. In the last step, we develop a novel way to present the information captured by the metamodel as a set of intelligible IF–THEN rules. For illustration, we use the FluTE model, which is an individual‐based influenza epidemic model. We observe that the number of daily applicable vaccines determines the success of an intervention strategy the most. Another critical observation is that when the daily available vaccines are constrained, nonpharmaceutical strategies should be incorporated to reduce the extent of the outbreak.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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