A comprehensive study of mobility functioning information in clinical notes: Entity hierarchy, corpus annotation, and sequence labeling.

Background: Secondary use of Electronic Health Records (EHRs) has mostly focused on health conditions (diseases and drugs). Function is an important health indicator in addition to morbidity and mortality. Nevertheless, function has been overlooked in accessing patients' health status. The World Hea...

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Publicado en:International Journal of Medical Informatics Vol. 147
Autores principales: Thieu, Thanh, Maldonado, Jonathan Camacho, Ho, Pei-Shu, Ding, Min, Marr, Alex, Brandt, Diane, Newman-Griffis, Denis, Zirikly, Ayah, Chan, Leighton, Rasch, Elizabeth
Formato: research tables/charts Journal Article
Publicado: Elsevier B.V. Mar2021
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: International Journal of Medical Informatics
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      dt: Mar2021
      vid: 147
      pid: 467
      pub: Elsevier B.V.
      place: New York, New York
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        148168362
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        148168362
        10.1016/j.ijmedinf.2020.104351
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        atl: A comprehensive study of mobility functioning information in clinical notes: Entity hierarchy, corpus annotation, and sequence labeling.
      aug:
        au:
          Thieu, Thanh
          Maldonado, Jonathan Camacho
          Ho, Pei-Shu
          Ding, Min
          Marr, Alex
          Brandt, Diane
          Newman-Griffis, Denis
          Zirikly, Ayah
          Chan, Leighton
          Rasch, Elizabeth
        affil: Oklahoma State University, Stillwater, OK, United States
      sug:
        subj:
          Natural Language Processing
          Human
          Comparative Studies
          Multicenter Studies
          Evaluation Research
          Validation Studies
          Funding Source
      ab: Background: Secondary use of Electronic Health Records (EHRs) has mostly focused on health conditions (diseases and drugs). Function is an important health indicator in addition to morbidity and mortality. Nevertheless, function has been overlooked in accessing patients' health status. The World Health Organization (WHO)'s International Classification of Functioning, Disability and Health (ICF) is considered the international standard for describing and coding function and health states. We pioneer the first comprehensive analysis and identification of functioning concepts in the Mobility domain of the ICF.Results: Using physical therapy notes at the National Institutes of Health's Clinical Center, we induced a hierarchical order of mobility-related entities including 5 entities types, 3 relations, 8 attributes, and 33 attribute values. Two domain experts manually curated a gold standard corpus of 14,281 nested entity mentions from 400 clinical notes. Inter-annotator agreement (IAA) of exact matching averaged 92.3 % F1-score on mention text spans, and 96.6 % Cohen's kappa on attributes assignments. A high-performance Ensemble machine learning model for named entity recognition (NER) was trained and evaluated using the gold standard corpus. Average F1-score on exact entity matching of our Ensemble method (84.90 %) outperformed popular NER methods: Conditional Random Field (80.4 %), Recurrent Neural Network (81.82 %), and Bidirectional Encoder Representations from Transformers (82.33 %).Conclusions: The results of this study show that mobility functioning information can be reliably captured from clinical notes once adequate resources are provided for sequence labeling methods. We expect that functioning concepts in other domains of the ICF can be identified in similar fashion.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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