Intake of Calanus finmarchicus oil for 12 weeks improves omega-3 index in healthy older subjects engaging in an exercise programme.

The n-3 PUFA, EPA and DHA, play an important role in human health. As the intake of EPA and DHA from the diet is often inadequate, supplementation of those fatty acids is recommended. A novel source of n-3 PUFA is Calanus finmarchicus oil (CO) which contains fatty acids mainly bound in wax esters. T...

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Publicado en:British Journal of Nutrition Vol. 125; no. 4; pp. 432 - 440
Autores principales: Wasserfurth, Paulina, Nebl, Josefine, Boßlau, Tim Konstantin, Krüger, Karsten, Hahn, Andreas, Schuchardt, Jan Philipp
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Cambridge University Press 2/28/2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2/28/2021
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      pub: Cambridge University Press
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        10.1017/S0007114520002809
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        atl: Intake of Calanus finmarchicus oil for 12 weeks improves omega-3 index in healthy older subjects engaging in an exercise programme.
      aug:
        au:
          Wasserfurth, Paulina
          Nebl, Josefine
          Boßlau, Tim Konstantin
          Krüger, Karsten
          Hahn, Andreas
          Schuchardt, Jan Philipp
        affil: Faculty of Natural Sciences, Institute of Food Science and Human Nutrition, Leibniz University Hannover, 30167 Hannover, Germany
      sug:
        subj:
          Food Intake In Old Age
          Oils Pharmacodynamics
          Plankton
          Fatty Acids, omega-3
          Exercise
          Human
          Esterases
          Body Mass Index
          Middle Age
          Aged
          Descriptive Statistics
          Randomized Controlled Trials
          Random Assignment
          Dietary Supplementation
          Male
          Female
          Data Analysis Software
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: The n-3 PUFA, EPA and DHA, play an important role in human health. As the intake of EPA and DHA from the diet is often inadequate, supplementation of those fatty acids is recommended. A novel source of n-3 PUFA is Calanus finmarchicus oil (CO) which contains fatty acids mainly bound in wax esters. To date, no data are available on the effects of long-term intake of this marine oil on n-3 PUFA blood levels. Therefore, the aim of this study was to evaluate the effect of CO on the n-3 PUFA blood levels using the omega-3 index (O3I). The data originate from a larger randomised controlled trial. For this analysis, samples from seventy-two participants (59·2 (sd 6·2) years, BMI 27·7 (sd 5·28) kg/m2) were analysed. Of those, thirty-six performed 2×/week exercise and received 2 g of CO, which provided 124 mg stearidonic acid (SDA), 109 mg EPA and 87 mg DHA daily (EXCO group), while the other group performed exercise only (EX group) and served as a control for this analysis. The O3I increased from 6·07 (sd 1·29) % at baseline to 7·37 (sd 1·10) % after 12 weeks within the EXCO group (P < 0·001), while there were no significant changes in the EX group (6·01 (sd 1·26)–6·15 (sd 1·32) %, P = 0·238). These data provide first evidence that wax ester-bound n-3 PUFA from CO can significantly increase the O3I despite relatively low EPA + DHA amounts. Further, the effects of exercise could be excluded.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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